Comment · Wed, December 9, 2020 · ND Owner
⚠️ NEW PRODUCT ALERT | High Potency Milk Thistle Capsules | 200mg of Silymarins from Silybum marianum ⚠️
Original post in this thread
NootropicsDepotCom · 32 points
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High Potency Milk Thistle Capsules | 200mg of Silymarins from Silybum marianum
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What they were answering
iwantmyownname · 4 points
If you mean percentage of silymarins, you get roughly 40% silymarins in the regular milk thistle powders, (4:1) which comes out at 100mg~ for a 250mg dose
This gives double that 200mg, so it's basically just two doses of the regular milk thistle powder but in one capsule
Which is very likely what they've done anyway, because capsules have been to my knowledge absent since the initial release of the powder
u/MisterYouAreSoDumb · ND Owner
Also, keep in mind that every single other milk thistle product we tested on the market failed for label claims. They were all universally lower in silymarins than they claimed. Ours is 100% validated at 200mg/capsule with proper HPLC assay. This means that ours has the highest silymarins per capsule out of every product we tested. NOW claims 300mg, but we tested it at 172mg and 168mg in our two sample preps. Pure Encapsulations claims 250mg, but we got 124mg and 125mg. Puritan's Pride claims 175mg, but we only got 60mg and 64mg. Life Extension claims 100mg, but we only got 56mg and 61mg. Jarrow claims 150mg per cap, but we only found 94mg and 94mg. Bulk Supplements had half the silymarins they claimed in their powder. The issue is that everyone is using "80% silymarins" milk thistle extracts, but that uses UV-VIS for the assay. That massively overstates the content. When you properly test it using HPLC/UPLC, you get about half that. It's just like bacopa. Everyone is massively overstating the silymarins content, just like people overstate the bacopaside content. UV-VIS is NOT an accurate assay method for complex botanicals. You need chromatographic separation to accurately assay the actives.
This is the really shitty part for us. If you just take the companies' word for it, it looks like we have less silymarins. However, we actually have the most out of anyone that we tested. It's just everyone else is mislabeling their products. So we get screwed because we are the only ones properly testing and labeling their milk thistle.