Comment · Sat, July 11, 2020 · ND Owner

Supplements to counter-balance Lions mane’s potential side effects?

Original post in this thread

faxmulder · 6 points

Hi guys,

which are the best supplements to pair with lion’s mane? My issues are mild anxiety, pessimistic attitude, brain fog/lack of focus and overthinking.

I’m interested because it seems they could help also in modulating the immune response (I have an autoimmune disease causing itching and inflammation on scalp).

In order to balance potential anti-androgen effects, such as loss of libido, I was thinking about pairing LM with something “pro testosterone/libido”, such as ashwagandha, cordyceps, sulbutiamine, maca, boron, shilajit (plus tongkat ali, when it will be available).

I know that there are no human studies but I’ve seen some anecdotal experiences. I’m concerned about LM potential downsides also because recent bloodworks showed that I have low luteinizing hormone LH (I have also varicocele).

This strategy could work? Do you have any experience about taking LM alongside these supplements?

For my issues I’m considering also other mushrooms (mainly chaga and white jelly), magnolia bark, nigella sativa, polygala, CBD oil and maybe kanna.

Thanks!

What they were answering

faxmulder · 2 points

Interested in getting /u/MisterYouAreSoDumb feedback as well

u/MisterYouAreSoDumb · ND Owner

Cordyceps, tongkat ali, KSM-66, and shilajit are the ones to combine with it. That will get your motor running.

Other MYASD lines in this thread

Related in the archive

Commentr/NootropicsDepotJul 10, 2025Botanicals & Q&AND Owner

Ok Amazon vs ND site saffron edition for

Replying to confused-caveman · Are you targeting Thorne customers as they've demolished their research team and you're (nearly?) essentially one of a kind at this point?

I guess we should be. Truth be told, marketing has always been our weakest link. I honestly hate the retail side of this industry. All the bad actors and lies. All the shady tactics and entrenched players. The fact that

10Lion’s maneTongkat aliShilajitCordyceps

Commentr/NootropicsDepotDec 20, 2020Nootropics DepotND Owner

A few doubts about preworkout stack

Stick to just agmatine. Most people find that to be sufficient without another source of arginine. Taurine, cordyceps, and beta alanine are good, though. >Adding something else for energy, such as dynamine or a B comple

6Tongkat aliAshwagandhaAgmatineCOA

Commentr/NootropicsDepotNov 4, 2020Nootropics DepotND Owner

Fat burning supplements

Replying to faxmulder · Thanks man, *much* appreciated. I hope that berberine capsules will be back soon - I prefer to wait for them since IIRC you said that the powder is one of the worst tasting (along…

1) Yes, since multiple women in our office have been raving at how much fat they have lost even just on OptimALA, our enteric EGCG, and hesperidin. 2) Tongkat, 100%. Increasing testosterone will lead to all the benefits

4Tongkat aliAshwagandhaPolygalaAgmatine

Commentr/NootropicsDepotNov 7, 2020Nootropics DepotND Owner

Effects of Tongkat Ali on body comp/exercise?

Replying to paisleyno2 · Hey - great experiences with ND. Thank you for being active on Reddit. Have recommended ND to friends and family. I just started Tongkat 10% from ND. 1. What else have you noti…

1) Tongkat has improved my energy and mood levels, too. 2) I got acute effects, but I would say they were really apparent after a week. 3) I take one capsule of 2% and one tablet of 10% in the morning. >I also a bunc

2Lion’s maneTongkat aliAshwagandhaAgmatine

Commentr/NootropicsDepotNov 22, 2020Nootropics DepotND Owner

What mood boosters ACTUALLY work out there?

It's going to depend on the person. What works best for one person might do nothing for you, or have side effects. We like to talk in generalities, but people's brain chemistries vary a lot more than most realize. So fin

35Lion’s maneTongkat aliAshwagandhaPolygala

Commentr/NootropicsDepotAug 26, 2020Nootropics DepotND Owner

Ginger-Degraded Collagen Hydrolysate (GDCH) increases GDNF/CNTF in hippocampus in mice and increases dopamine activity leading to antidepressant effects

Replying to 12ealdeal · Is ND a company that tests the legitimacy and quality for there products or something?

LOL, you are on our subreddit... https://www.reddit.com/r/NootropicsDepot/comments/ec0xlt/lab_update_nederman_gas_extraction_arms/ https://www.reddit.com/r/NootropicsDepot/comments/esfye6/lab_update_waters_uplcms_and_

12Lion’s maneAshwagandhaShilajit