Comment · Wed, May 20, 2020
MYASD, taking pills on empty stomach doesn’t matter right?
What they were answering
arrialexa · 1 points
Do you mean sulb is a P-gp inhibitor like curcumin? or P-gp disrupts it's efficacy?
u/MisterYouAreSoDumb
I meant P-glycoprotein substrate. Sulbutiamine is rapidly and completely absorbed in the GI tract, though. It's affinities toward P-glycoprotein don't seem to affect its GI absorption. However, it could affects it's clearance time. The half life is 5 hours. It could be longer with a p-Glycoprotein inhibitor.