Comment · Wed, September 19, 2018 · Natrium Health & Nootropics Depot
Studies show that Amphetamine sensitization occurs in Healthy Individuals after just 3 intermittent dosing with 20mg d-amphetamine. Is it dangerous?
Original post in this thread
tronatula · 101 points
[[full text] The amphetamine-induced sensitized state as a model of schizophrenia](https://drive.google.com/open?id=1BM1QZHpVcwzG9bEtRLWli5vn5KU0_qTz)
[[full text] Modeling Sensitization to Stimulants in Humans](https://jamanetwork.com/journals/jamapsychiatry/fullarticle/209916)
[[full text] Enhanced behavioral response to repeated d-amphetamine and personality traits in humans](https://drive.google.com/file/d/1J1r2AUg4b3ZraHDsx3wyS6PyTWcfBIfS/view?usp=sharing)
Dosages in 3 studies above are ~20mg d-amphetamine (Dexerine) on day 1,3 and 5. No need for microdosing and the phenomenon persists for at least 1 year. The question is:
If Amphetamine sensitization is indeed dangerous, why is it rarely mentioned in studies about Prescription Stimulant Medication Misuse? Why they keep recruit healthy individuals to make them sensitized? Why is amphetamine approved for ADHD? Isn't it too easy to get amphetamine sensitization?
What they were answering
rem28 · 3 points
What is considered abuse? Days on it? Dosage?
u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot
That would depend on the person. Someone with diagnosed ADHD that really needs it to function is going to be taking a lot more than someone using it to study. A normal person using it daily would probably be considered abuse, IMO. That would not be the case for someone with ADHD. However, someone with ADHD taking large doses on the weekend to go out partying would.