Skip to content
MYASDArchive
Archive/r/Nootropics

Comment · Fri, September 21, 2018 · Natrium Health & Nootropics Depot

Studies show that Amphetamine sensitization occurs in Healthy Individuals after just 3 intermittent dosing with 20mg d-amphetamine. Is it dangerous?

Original post in this thread

tronatula · 101 points

[[full text] The amphetamine-induced sensitized state as a model of schizophrenia](https://drive.google.com/open?id=1BM1QZHpVcwzG9bEtRLWli5vn5KU0_qTz)

[[full text] Modeling Sensitization to Stimulants in Humans](https://jamanetwork.com/journals/jamapsychiatry/fullarticle/209916)

[[full text] Enhanced behavioral response to repeated d-amphetamine and personality traits in humans](https://drive.google.com/file/d/1J1r2AUg4b3ZraHDsx3wyS6PyTWcfBIfS/view?usp=sharing)

Dosages in 3 studies above are ~20mg d-amphetamine (Dexerine) on day 1,3 and 5. No need for microdosing and the phenomenon persists for at least 1 year. The question is:

If Amphetamine sensitization is indeed dangerous, why is it rarely mentioned in studies about Prescription Stimulant Medication Misuse? Why they keep recruit healthy individuals to make them sensitized? Why is amphetamine approved for ADHD? Isn't it too easy to get amphetamine sensitization?

What they were answering

kvist · 1 points

I take adderall just to be functional at work. And I take weekend break just to recoup my sleep that's lost due to insomnia induced by the substance. The weekend break practice does limit my social activity to some degree, but its been keeping my tolerance at bay for a few years. I don't regret.

u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot

If you are being prescribed it by a doctor, and need it to be functional, I would say there is nothing to regret about it.

Other MYASD lines in this thread

Related in the archive

Postr/NootropicsJul 18, 2023

Independent Lab Testing Results Of Supplements On The Market

Hey everyone, it's been a while since I have made a post in this sub. However, I saw a new research study today that I wanted to bring up. It highlights why my main mission over the past 10 years has been to not only adv

402152Dosing
Postr/NootropicsNov 27, 2013

Cerebral Health Pyritinol (New Test Results)

We have finally identified the substance that Cerebral Health was selling as pyritinol, which has sent one person to the hospital, and caused adverse reactions in half a dozen other people so far. The results are very su

13776Dosing
Postr/NootropicsFeb 28, 2013

Reddit Placebo Blinded Racetam Study

Well the time has finally come. My curiosity has finally expanded to real world effectiveness, not just pharmacological mechanisms. We are all aware of the countless anecdotes for the various nootropics out there. Many o

121166PiracetamAniracetamDosingRacetams
Commentr/DrugsNov 8, 2012

Research Suggests no Neurotoxicity in MDMA

**I'm going to copy what I wrote on another thread:** _____________________________________________________ YES! Keep your damn body temperatures down people! http://www.maps.org/publications/1998_malberg_1.pdf http:

597PiracetamMagnesiumQuercetinDosing
Commentr/NootropicsNov 19, 2014

My experiences with high dose (100mg+) tianeptine over a two month period

You need to start tapering off it now! You are not using it properly, and are going to cause yourself harm. Tianeptine is hard on the liver at those dosages. It is not meant to be taken at 650mg/day. Your usage is irresp

51TianeptineDosing
Commentr/NootropicsJun 30, 2020

Safe to Buy Now Food Supplements from Amazon?

Replying to [deleted] · [deleted]

Okay, scratch what I said. I just got some lab results back from NOW's milk thistle, and it failed our testing. It is only 70% of label claim! I literally bought NOW, Jarrow, and Life Extension in this test as our positi

45DosingMilk thistle