DEA to place Mitragyna speciosa (Kratom) and its active alkaloids mitragynine and 7-hydroxymitragynine into Schedule I on 30. September 2016.

The story behind the FDA raid of Nootropics Depot

Replying to ProperBeat · Priceplow is pretty biased guys Here's [a more objective description](https://www.justice.gov/usao-nh/pr/arizona-company-and-ceo-sentenced-illegal-distribution-tianeptine-and-othe…

That is not an objective description... This is a more objective description by the FDA and DOJ: https://www.justice.gov/usao-nh/pr/arizona-company-and-ceo-plead-guilty-distribution-drugs-not-approved-fda-and-will-pay-24

[META] Modafinil discussions should not be prohibited anymore. The hype around it has died down, and it is still one of the most effective and safest nootropics.

Replying to WhateverChomp · > Seriously, is there actually anything specific about modafinil that people here want to discuss? Everyone is rallying around the idea of discussing it, but nobody is actually giv…

>If somebody wants to talk about any of these in the context of cognitive enhancement, then let them. We already do. They just have to message us about it, or we might see it in the logs ourselves and approve it manuall

How fast does Agmatine Sulfate reduce tolerance?

Replying to PhantomZero77 · The reason I’m asking is because there have been numerous anecdotal reports about using agmatine to successfully reduce phenibut tolerance. You can find loads of them on r/quitting…

Tolerance is a very complex thing. However, we do have a lot of anecdotes about NMDA antagonists helping with many things. It's because the NMDA receptors are linked to many other receptor systems in the body, and they c

Phenibut. Wow. I never researched it entirely, but after helping someone with a few questions, I have been reading about it. This is terrifying. PLEASE Please read the phenibut wiki and keep reading the related separate properties wiki's. Read everything related to Phenibut.

Opioids can certainly alter the perceived noise level of your hearing. I have noticed that Kratom can make my tinnitus worse at times. I would more suspect the kratom for the hearing changes.

Picamilon vs Phenibut

Replying to Sigfund · I did not know that! Do you have a good resource for information on other kratom alkaloids? Suppose I should just start with wikipedia, that is cool.

http://www.kratom.net/content.php?49-List-of-alkaloids-identified-in-Mitragyna-speciosa-Kratom-and-their-known-or-potential-activity

I think I got my friend addicted to Phenibut

The GABA system is a dangerous one. Tolerance builds quickly, and withdrawal can be very bad; life threatening even. If you want something safer in the GABAnergic space, kava would be safer. I'd move to a different syst