DEA to place Mitragyna speciosa (Kratom) and its active alkaloids mitragynine and 7-hydroxymitragynine into Schedule I on 30. September 2016.

black seed oil (1 month update)

Replying to antitetico · As far as I understand, the extract from ND is just a worse value than the oil if it doesn't bug your stomach. Each capsule is labeled 200 mg, but only 5% of that is guaranteed to …

You're comparing our capsules to their bottled oil. That's not like-for-like. You should compare our capsules to their softgels, then compare our powder to their oil. If you take out all the cost of encapsulation, of cou

The story behind the FDA raid of Nootropics Depot

Replying to ProperBeat · Priceplow is pretty biased guys Here's [a more objective description](https://www.justice.gov/usao-nh/pr/arizona-company-and-ceo-sentenced-illegal-distribution-tianeptine-and-othe…

...continued... Now a little backstory here... we did sell tianeptine years prior. I explained it in the podcast, but I will reiterate some here. I went through a bad depression when I was younger, and almost took my li

Does Piracetam eventually stop working for everyone?

Replying to TheGophChauff · I've also recently been researching this exact topic. In fact, I was going to post a thread about exactly this sometime in the afternoon after reading extensively about Piracetam l…

There is no free lunch in life. This applies to most everything. Our body strives to maintain homeostasis. So when we alter that homeostasis with something like piracetam, there has to be some mechanism that will attempt

Please be cautious on orders from Botany.bio - mistakenly labeled (and therefore adulterated unknown substance) from product found in my last order.

Replying to thaw4188 · Yeah I get that, the whole industry is a nightmare. Some of the things ConsumerLabs has found are hair-raising. The thing is, *-right now-* their in-house lab seems on top of thin…

As long as I own Nootropics Depot, you don't have to worry about that. I'll go out of business before I'll compromise my ethics and cut corners on testing. Just ask any of my employees. Sometimes we just go out of stock

physiological opiate tolerance & dependence on Tianeptine?

It is a very mild μ-opioid agonist (Ki Human of 383±183 nM, and EC50 Human of 194±70 nM, and EC50 Mouse of 641±120 nM for G-protein activation). That is not its main mechanism of action, and only really comes into play i

Modafinil Tolerance: Possible Modes of Action

I can 100% confirm that the CYP3A4 induction from modafinil is substantial. At least it is for me. If I take modafinil in the morning, then take a substance that is metabolized by CYP3A4 (i.e. kratom), then the effects a