Comment · Tue, July 5, 2016

MK-677 availability??

Original post in this thread

justcheckinginn · 7 points

Hey Ceretropic

Do you have any idea when MK-677 will be in stock? I know purity is an issue from the previous posts, but i was wondering if you found a distributor that you might work with. If you have any info or update, that would be helpful.

thanks

What they were answering

londob5 · 2 points

Do you have NMR info?If you have the NMR file I can put it into acorn and take a look.
Also, this was a powder that you had analyzed, correct?
3% EtOAc is larger than expected, considering the source was presumably a commercial lab.
From the looks of the MK-677 molecule, the other solvent (my guess without a NMR/GCMS) is possibly DMF.

u/MisterYouAreSoDumb

We do not have an NMR, unfortunately. We have an HPLC and FTIR.

Dimethylformamide could be it as well. That is used in one of the synthesis methods I am seeing.

Here is the paper where I am seeing the synthesis method using DHM: A facile synthesis of the spiroindoline-based growth hormone secretagogue, MK-677

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