Comment · Sat, May 21, 2016 · Ceretropic & Nootropics Depot
Started taking KSM66, waking up every day at 6 AM regardless of when I go to bed.
Original post in this thread
particularindividual · 1 points
I've been taking it for 2 weeks and it's best supplement for stress I've ever taken, along with powdered magnesium. But it doesn't matter if I go to bed at 10 PM or 1 AM, I still get up within 5 minutes of 6 AM every single day. Previously I would get up anywhere between 6 AM and 8 AM.
Has anyone else had a similar effect? Does anyone have an idea of what could be happening here?
What they were answering
afriendindeeds · 1 points
I can do 7-8 hours with modafinil only. even then, my eyes show it. I feel really good with 9+, but I can't get that and still always go to sleep on time the next night. Been like this my entire life. I don't snore and I sleep soundly.
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
Sleep Duration and All-Cause Mortality: A Systematic Review and Meta-Analysis of Prospective Studies
In terms of prevention, consistently sleeping 6 to 8 h per night may therefore be optimal for health. However, sleeping 9 h or more per night may represent a useful diagnostic tool for detecting subclinical or undiagnosed co-morbidity. People reporting consistently sleeping 5 hours or less per night should be regarded as a higher risk group for all-cause mortality. A 12% increased risk of death in short sleepers, if causally related, would equate to over 6.3 million attributable deaths in the UK in people over 16 years of age and over 25 million attributable deaths in the US in people over the age of 20 years.
Duration of sleep should be regarded as an additional behavioral risk factor or risk marker heavily determined by the environment and possibly amenable to modification through both education and counselling as well as through measures of public health. The latter would aim at favorable modifications of physical and working environments to allow sufficient sleep and avoid habitual and sustained sleep deprivation.
Another one looking at just cardiovascular disease:
Short duration of sleep was associated with a greater risk of developing or dying of CHD (RR 1.48, 95% CI 1.22–1.80, P < 0.0001), stroke (1.15, 1.00–1.31, P = 0.047), but not total CVD (1.03, 0.93–1.15, P = 0.52) with no evidence of publication bias (P = 0.95, P = 0.30, and P = 0.46, respectively). Long duration of sleep was also associated with a greater risk of CHD (1.38, 1.15–1.66, P = 0.0005), stroke (1.65, 1.45–1.87, P < 0.0001), and total CVD (1.41, 1.19–1.68, P < 0.0001) with no evidence of publication bias (P = 0.92, P = 0.96, and P = 0.79, respectively).
Conclusion Both short and long duration of sleep are predictors, or markers, of cardiovascular outcomes.
Another one looking at sleep duration and inflammation:
Sleep duration and biomarkers of inflammation.
RESULTS: In this cohort, mean (SD) habitual sleep duration based on self-report was 7.6 (1.6) h and mean sleep duration by polysomnography (PSG) on the night prior to blood sampling was 6.2 (1.3) h. After adjusting for obesity and apnea severity, each additional hour of habitual sleep duration was associated with an 8% increase in C-reactive protein (CRP) levels (P=0.004) and 7% increase in interleukin-6 (IL-6) levels (P=0.0003). These associations were independent of self-reported sleepiness. In contrast, PSG sleep duration was inversely associated with tumor necrosis factor alpha (TNFa) levels. For each hour reduction in sleep, TNFalpha levels increased by 8% on average (P=0.02). Sleep duration was not associated with IL-1 or IL-10.
CONCLUSIONS: Increases in habitual sleep durations are associated with elevations in CRP and IL-6 while reduced PSG sleep duration is associated with elevated TNFa levels. Activation of pro-inflammatory pathways may represent a mechanism by which extreme sleep habits affect health.
Another on sleep duration and diabetes:
Sleep duration as a risk factor for the development of type 2 diabetes.
RESULTS: Men reporting short sleep duration (< or =5 and 6 h of sleep per night) were twice as likely to develop diabetes, and men reporting long sleep duration (>8 h of sleep per night) were more than three times as likely to develop diabetes over the period of follow-up. Elevated risks remained essentially unchanged after adjustment for age, hypertension, smoking status, self-rated health status, education, and waist circumference (RR 1.95 [95% CI 0.95-4.01] for < or =5 h and 3.12 [1.53-6.37] for >8 h). RRs were altered considerably for the two extreme sleep groups when adjusted for testosterone (1.51 [0.71-3.19] for < or =5 h and 2.81 [1.34-5.90] for >8 h), suggesting that the effects of sleep on diabetes could be mediated via changes in endogenous testosterone levels.
CONCLUSIONS: Short and long sleep durations increase the risk of developing diabetes, independent of confounding factors. Sleep duration may represent a novel risk factor for diabetes.
So if you are finding yourself needing to sleep 9 hours or more a night to feel rested, I would speak to your doctor about it, and possibly have a sleep study done. There is clear evidence that sleeping less/more than 6-8 hours a night being an indicator of serious health issues, and the risk of shortened life span.