Comment · Fri, April 29, 2016 · Ceretropic & Nootropics Depot
Would taking SEMAX prevent some of the benefits of exercise? Would it potentiate others?
Original post in this thread
Noobsessed · 14 points
So SEMAX appears to be a good drug to prevent hypoxia related neuronal damage. As such, it seems plausible that taking semax during intense aerobic exercise would be a good way to reduce the damage that could potentially take place with it.
However, would it reduce the expression of VEGF? If that were the case, what would you say is better: less hypoxia or more VEGF? It seems like a part of the VEGF that acts on the brain is actually produced outside of it so my guess is that taking SEMAX before exercise would produce a net gain. I'm no medical authority though, so I ask /r/Nootropics.
My other question is if SEMAX, being that it increases the response to amphetamine, would be beneficial in regards to the motivation boost produced by exercise through dopamine and beta-phenilalanine increase.
Do you see any other reason to take SEMAX apart from the previous? Has anyone experimented with the effects of SEMAX on mood or performance while exercising?
What they were answering
flamingwarbear · 1 points
You said a lot of stuff I don't understand so I'm going to take it as disrespect. Is there are reason you chose Montelukast? I've been prescribed Advair and have been on it for 2 months. If we're going to 'hack' asthma, has your knowledge brought you to any conclusions?
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
You said a lot of stuff I don't understand so I'm going to take it as disrespect.
Disrespect?
I've been prescribed Advair and have been on it for 2 months.
Advair is a long-acting beta-adrenergic agonist. Basically it stimulates your adrenergic system, causing the inflammation in your lungs to go down. It's not an ideal way of fixing the issue, because it is treating the symptom, not the cause.
Is there are reason you chose Montelukast?
Montelukast is a leukotriene receptor antagonist. That is blocking the binding of leukotrienes, which are produced by your immune system to cause bronchoconstriction and mucous secretion. Blocking them means that you stop that signaling that is leading to the asthma. Corticosteroids are more effective for those with full-on asthma. However, leukotriene receptor antagonists are much better for those with mast cell disorders, which is what I have, and what causes my activity-induced asthma. If I take Montelukast before exercise, I have zero issues whatsoever. It's like a light switch for my issues.