Comment · Fri, April 29, 2016 · Ceretropic & Nootropics Depot
Would taking SEMAX prevent some of the benefits of exercise? Would it potentiate others?
Original post in this thread
Noobsessed · 14 points
So SEMAX appears to be a good drug to prevent hypoxia related neuronal damage. As such, it seems plausible that taking semax during intense aerobic exercise would be a good way to reduce the damage that could potentially take place with it.
However, would it reduce the expression of VEGF? If that were the case, what would you say is better: less hypoxia or more VEGF? It seems like a part of the VEGF that acts on the brain is actually produced outside of it so my guess is that taking SEMAX before exercise would produce a net gain. I'm no medical authority though, so I ask /r/Nootropics.
My other question is if SEMAX, being that it increases the response to amphetamine, would be beneficial in regards to the motivation boost produced by exercise through dopamine and beta-phenilalanine increase.
Do you see any other reason to take SEMAX apart from the previous? Has anyone experimented with the effects of SEMAX on mood or performance while exercising?
What they were answering
flamingwarbear · 2 points
I first tried Semax a week ago and incorporated it into my running regimen. I've run twice just before dosing 100mcg of Semax and found that while it gave me an extra boost it also potentiated my anxiety from my mild asthma while running so I've since wrote off Semax. As an aside, rather than make a new topic, are the other Semax compounds less edgy?
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
N-acetyl Semax is more edgy, based on most people's anecdotes. N-Acetyl Semax Amidate is usually reported to be more anxiolytic. However, anecdotal response varies a bit from person to person.
Also, Semax increases immune response. That's good for boosting the immune system. However, it could be what is setting off your mild asthma. Semax alters the expression of genes that modulate the amount and mobility of immune cells, and enhances the expression of genes that encode chemokines and immunoglobulins. Chemokines, along with interleukin-13, are thought to be central to the mechanism that causes asthma. Also, Immunoglobulin E is central to the inflammatory response in the lungs. So Semax might set off your asthma. I have activity-induced asthma, but I usually take Monteleukast before activity, and that prevents any breathing issues.