Comment · Sat, August 22, 2015 · Ceretropic
Four(-ish) questions about NA-Selank!
Original post in this thread
srubek · 10 points
ONE
It is widely accepted that NA-Selank's calming properties are attributable to its "induction of the metabolism of serotonin," right?
So my first real question is, what does that mean? Does it induce metabolism of serotonin into serotonin metabolites; or does it metabolize potential precursors into serotonin itself?
If the answer is the latter, then does this result in a net increase in serotonergic synaptic activity, or just an increase in synthesis & storage of it in the presynaptic vesicles?
-----------------------------------------------
TWO
I'm also curious by what all mechanisms this is considered a nootropic...
So secondly, is its release of BDNF/NGF exclusive to the hippocampus?
-----------------------------------------------
THREE
I've noticed that NA-Semax Amidate has an anxiolytic component to it; an effect that its non-amidated version is missing...and I would like to have that anxiolysis at night but without Semax's stimulation...hence my third big question:
Would it potentially be more effective, anxiolytic, and/or longer lasting with an 'amidated' C-terminus or other...terminus? (please forgive and correct my technical errors--I prefer precision, and…
What they were answering
SyntacticSugars · 2 points
would you suspect there would be any up/down regulation of enkephaline-degrading ezymes induced by (long term(6-12 months)) use of selank?
glad to hear NA-selank-amidate is in the works!
u/MisterYouAreSoDumb · Ceretropic
It's theoretically possible. However, I do not see any evidence that it does happen.