Comment · Tue, April 21, 2015 · Ceretropic
Best you've ever felt from nootropics - what did you take?
What they were answering
adderallworks · 1 points
The issue is that you would need to get permission for that ahead of time, and control for other factors. That would be a serious challenge.
It doesn't matter. It can still be determined, measured and substantiate neurotoxicity.
Those studies are not funded by the pharma companies, though. Also, they could just point to the fact that it was being abused. With profit as a factor, I highly doubt the pharma companies are going to fund studies that might show long-term damage. We would need a third party to fund it.
It doesn't matter. Then why don't non-pharmaceutical companies fund studies that show neurotoxicity in humans?
Also, they could just point to the fact that it was being abused
Well then that wouldn't be a scientific study.
u/MisterYouAreSoDumb · Ceretropic
Measuring something, without a baseline and controls, is not going to tell us anything useful. Did that person use other substances during their life? Did they have other genetic variations that would confound the results? It's just a very hard thing to study in humans. Then you have to find someone willing to donate their brain after they die. You also have to take into account cause of death, and the age they were went they died. You might be waiting a pretty long time to get a significant sample size. Primate models are the closest thing we have.
Then why don't non-pharmaceutical companies fund studies that show neurotoxicity in humans?
Money. A study to unequivocally prove neurotoxicity in humans, is going to cost an absolute ungodly amount of money. Just that primate study probably cost a ton. Someone needs to fund it. There is a lot of money in ADHD meds. There is not a lot of money in showing risks/damage.
Well then that wouldn't be a scientific study.
The studies showing damage from abuse are certainly scientific. It's just the pharma companies have an excuse for why that does not apply to prescription dosing. A study showing damage at therapeutic dosages, would cause a lot of issues for them. There's more money in showing things are safe, rather than showing things are damaging; that is, unless you are talking about schedule 1 substances. Then there seems to be more than enough government money to try and show damage. Schedule 2? Not so much.