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Comment · Sat, July 26, 2014 · Ceretropic

SEMAX as an antidepressant?

Original post in this thread

dilated_student · 6 points

Since both SEMAX and ketamine have been shown to increase BDNF singificantly after adminstration.[1][2]
Furthermore, BDNF increase is suggested as a biomarker relevant to antidepressant response for ketamine[2] and other more common antidepressants.[3]

[1]. http://www.ncbi.nlm.nih.gov/pubmed/16996037
[2]. http://www.ncbi.nlm.nih.gov/pubmed/24103211
[3]. http://www.ncbi.nlm.nih.gov/pubmed/21749907

Soo, did anyone notice any kind of effects on depression/low mood from SEMAX?

NOTE: I don't have any experience with SEMAX.

What they were answering

dilated_student · 1 points

How do you compare its mood boosting quality to tianeptine (not combined)?

u/MisterYouAreSoDumb · Ceretropic

SEMAX is more of a natural stimulation feeling. Tianeptine is more of a mood enhancer. I would say that tianeptine increases your mood more noticeably, but can make you a little tired. Combining it with SEMAX helps bring some stimulation to counter that. They go really well together.

But you cannot go wrong with tianeptine for mood enhancement. Most people respond very well to it.

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