Comment · Sat, February 14, 2026 · Nootropics Depot & Natrium Health
My top 10 takeaways from Rhonda Patrick's new episode about NAD precursor supplements (NR vs. NMN)
Original post in this thread
biohacker045 · 66 points
What's up boys. I just finished Rhonda Patrick's new episode with Charles Brenner (the guy who discovered nicotinamide riboside, AKA NR). Here's everything I learned. My top 10 takeaways:
1. Ok so first off, buying an "NAD supplement" on Amazon is basically a waste of money. You're much better off buying a precursor (like NR) and supplementing with that to boost NAD. (timestamp)
2. NR is way more effective than that other NAD precursor (NMN). So I'm not an expert but I think NMN is the one David Sinclair preaches about. Charles stressed multiple times that NMN has to be broken down into NR to get into the cell... so you're just better off taking NR. (timestamp)
3. The absolute biggest benefit of taking NR (for healthy people) is exercise recovery. Apparently used to be common in the Patriots locker room under Belichick. So Brady was definitely taking it. There's photos of Charles Brenner and Belichick out there somewhere. (timestamp)
4. Rhonda said she is taking Tru Niagen at the moment (NR) and has been f…
What they were answering
Warren_sl · 2 points
I don’t know if they’re using CellG8 anymore they removed all references to them. I think the gel
was always a different manufacturer but I’m unsure who. Maybe EffePharm?
u/MisterYouAreSoDumb · Nootropics Depot & Natrium Health
Could be. I'd have to get another sample from them and test again. Whatever it was a year and a half ago was not a liposome. I've been pretty vocal about calling that out, so maybe people have finally switched suppliers to a real one. I didn't end up buying the Nanosight. We just had Malvern bring it and do a demo in our lab on a bunch of samples we had. I still might buy it at some point. We would really need both the Nanosight and a cryoTEM to ensure 100%. However, a cryoTEM runs $500K at the low end, and $15M at the high end. Bonkers costs. The Waters Xevo TQ-S Micro triple quad mass spec I just bought is a $437,000 machine. However, I got us a good deal the week before year end, to get their end of year numbers up, so I didn't pay full price. However, that's the most expensive single machine I have bought to date. I'll need to sell a LOT more product to justify some of these more specialized machines.