Comment · Wed, February 11, 2026 · Nootropics Depot & Natrium Health
My top 10 takeaways from Rhonda Patrick's new episode about NAD precursor supplements (NR vs. NMN)
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biohacker045 · 66 points
What's up boys. I just finished Rhonda Patrick's new episode with Charles Brenner (the guy who discovered nicotinamide riboside, AKA NR). Here's everything I learned. My top 10 takeaways:
1. Ok so first off, buying an "NAD supplement" on Amazon is basically a waste of money. You're much better off buying a precursor (like NR) and supplementing with that to boost NAD. (timestamp)
2. NR is way more effective than that other NAD precursor (NMN). So I'm not an expert but I think NMN is the one David Sinclair preaches about. Charles stressed multiple times that NMN has to be broken down into NR to get into the cell... so you're just better off taking NR. (timestamp)
3. The absolute biggest benefit of taking NR (for healthy people) is exercise recovery. Apparently used to be common in the Patriots locker room under Belichick. So Brady was definitely taking it. There's photos of Charles Brenner and Belichick out there somewhere. (timestamp)
4. Rhonda said she is taking Tru Niagen at the moment (NR) and has been f…
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u/MisterYouAreSoDumb · Nootropics Depot & Natrium Health
There is a lot of BS around the ND vs NMN stuff right now, and a ton of propaganda from Tru Niagen. In fact, they are trying to get NMN banned again.
Bioscience Company Sues FDA Over Dietary Supplement Reversal
They are literally suing the FDA to try and get them to pull NMN from the market, even though it is found naturally in human breast milk, the very first foods humans eat after they are born.