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Comment · Mon, October 10, 2022 · ND Owner

⚠️ NEW PRODUCTS ALERT | Red Reishi Ultra Concentrated 9% Ganoderic Acids Extract Capsules, Salidrosol Tablets, & OmegaTAU V Capsules⚠️

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NDSocialMedia · 33 points

What they were answering

sebovarli · -2 points

prefer to use that extract because two Taiwanese trials in Alzheimer's and hearing loss patients
it is incredibly dysphoric // it does help Alzheimer's patients, but it does the opposite in healthy people

I looked and found one Italian and one Taiwan clinical trial, not 2 Taiwanese and nothing including hearing loss 🥺🥺

I am a bubbly person and not depressed ever, and the orevida extracts that you called trash did not cause negative effect but postive only, including increase in libido and immune health

IMO you are overeacting and projecting your opinion and anecdote as a fact here which is not okay 😯😯

u/MisterYouAreSoDumb · ND Owner

It feels like you just want to argue with me...

Effects of erinacine A-enriched Hericium erinaceus on elderly hearing-impaired patients: A double-blind, randomized, placebo-controlled clinical trial

Prevention of Early Alzheimer’s Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study

Those are the two Taiwanese papers I am referring to. I have personally beta tested the extract used in those two clinical studies. This is what I am referring to when I say it is dysphoric. We also know why it is dysphoric now as well, since we tested the extract and found a compound that hits the kappa opioid receptor. This extract also did NOT CONTAIN erinacine-A, which is a big problem because it's in the title of both studies. Everyone reading those studies are going to assume erinacine-A is giving those effects, when we have proven the extract to not contain it. If you think this is me overreacting and projecting my opinion, well then I am not sure I can say much else to you. These are the first human clinical trials on lion's mane mycelium in history. You don't think the fact that the extract used in the studies doesn't contain what it claims to is a big deal?

Also, I'm the one projecting my opinion and relying an anecdotes?!? Your argument is literally: "Well I used the Oriveda stuff, and I liked it, so I am going to discount what you are saying. I am also a bubbly person, so who cares about depression?" That's the very definition of anecdotal evidence. The focus of our scientific work is not based on my personal effects. I just added that anecdote to the mix because I am one of the only people in the world that has actually tried the extract used in the two human clinical studies on liquid culture lion's mane mycelium. I am not even opposed to selling this extract. I personally wouldn't take it, but other people might like it. However, I would have to label it properly, and tell everyone it doesn't contain erinacine-A. The Taiwanese won't like that, as they think they made an erinacine-A standardized extract. There are a lot of political issues in the background on this situation. How would you feel as a researcher if you were the first to publish human clinical studies on something, and it later turned out your extract didn't contain what you thought? Imagine having to retract those papers. It's a big deal!

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