⚠️ NEW PRODUCTS ALERT | Pyridoxal-5 Phosphate Capsules, S-Acetyl L-Glutathione Capsules & Powder, & Astragaloside IV Capsules⚠️

Comment · Thu, August 18, 2022 · 18 pts

We are doing more astragalus products. This is just the first one. It's also the cheapest per mg astragaloside IV on the market at the moment. So more expensive than normal astragalus for sure, but the cheapest for astra

Comment · Thu, August 18, 2022 · 11 pts

Absolutely! I am personally combining it with OptiNAD+ daily. I am not taking carnosine, as that pushes me into anxiety with my current stack, but I am taking astragaloside IV daily now. It does add a bit more stimulatio

Comment · Thu, August 18, 2022 · 16 pts

We didn't manually delete it. It was caught by the automod. I just read that study, and I am leaning towards it being meaningless. Look at the actual data. The people using higher doses of B12 and B6 had more physical

Comment · Thu, August 18, 2022 · 11 pts

There is cool research there with astragaloside IV. However, I always take my Zrytec, so it is hard for me to objectively assess the histamine thing. Maybe I will try to skip some doses and see. I just hate doing that, b

Comment · Fri, August 19, 2022 · 10 pts

Perhaps on some. However, if you are more active, you are more likely to be in scenarios where you might fracture your hip. It's absolutely a confounding variable. If you are sedentary, you are less likely to be in situa

Comment · Fri, August 19, 2022 · 2 pts

Sure, moderate-to-vigorous physical activity is correlated with better bone mass, especially in men. It's less of a correlation in women, though. The study we are commenting on was in women. https://www.ncbi.nlm.nih.gov

Comment · Fri, August 19, 2022 · 10 pts

You know what, after reading a bit more, I think there is something here. Vitamin B6 seems to modulate steroid hormones. Lower B6 levels actually corresponds to higher sensitivity to steroid hormones. This means people w

Comment · Fri, August 19, 2022 · 3 pts

It's the only one that has reliably worked for my histamine issues over the past 20 years. I've tried every one you can think of. I always go back to cetirizine.

Comment · Fri, August 19, 2022 · 7 pts

I take it in the morning on an empty stomach. I fast 23 hours a day, so pretty much everything I take is on an empty stomach.

Comment · Fri, August 19, 2022 · 5 pts

Carnosine seems to have a higher propensity to push me into anxious states. I am not sure why, but I do notice it. Astragaloside IV and carnosine are very similar, otherwise. They both are neuroprotective. They both posi

Comment · Fri, August 19, 2022 · 5 pts

I am not sure of any direct mechanism for sexual health and Astragaloside IV. It does seem to positively affect mood in some models, though. [Anti-anxiety and antidepressant-like effects of astragaloside IV and saponins

Comment · Fri, August 19, 2022 · 3 pts

Yeah, I actually read further and did some more research, and I do think there is something to the B6 link. https://www.reddit.com/r/NootropicsDepot/comments/wrou6j/new_products_alert_pyridoxal5_phosphate_capsules/ikyu

Comment · Fri, August 19, 2022 · 4 pts

Well with testosterone it seems a bit more complex. https://www.sciencedirect.com/science/article/abs/pii/0022473184903480 It seems lower B6 levels actually lowers testosterone. So yes, it will sensitize testosterone r

Comment · Mon, August 22, 2022 · 3 pts

Well that's an issue with pyridoxine, but not P5P. So the two situations are different. Taking higher doses of pyridoxine actually lowers P5P levels, due to the salvage pathway. The prevailing theory is that is lowering

Comment · Tue, August 23, 2022 · 3 pts

I just looked at the Pure Encapsulations B complex. They are mixing pyridoxine HCL and P5P together in an unknown ratio. The ironic thing is that pyridoxine intake can actually lower P5P, which can cause neuropathy. No i

Comment · Wed, August 24, 2022 · 2 pts

No, I have not had any serious injuries. I did get some whiplash when I crashed an ATV in the sand dunes in California. I passed out and I was taken to the hospital on a immobilizing stretcher, but CT scans showed no dam

Comment · Wed, August 24, 2022 · 2 pts

Yeah, tried that one as well. It works okay, just not as well as cetirizine for me.

Comment · Wed, August 24, 2022 · 1 pts

Ohh, definitely before. It's a genetic thing. My mom had it when she was really young as well.

Comment · Fri, September 23, 2022 · 1 pts

Astragaloside IV lengthens telomeres.