Comment · Fri, September 25, 2020 · ND Owner
NMN, Niacin, NAD +, and Addiction
Original post in this thread
[deleted] · 5 points
I was really fascinated to see studies supporting the idea that NAD therapy could be a used pretty straightforwardly as a treatment for addiction:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278809/
It seems clear that NMN is one of the best oral routes to raise NAD levels, but there also seems to be evidence that straight niacin can raise NAD levels, at least in individuals considered deficient:
https://pubmed.ncbi.nlm.nih.gov/32386566/
The substance itself, and its systemic effects is quite exciting, but even more wild is that the founder of Alcoholics Anonymous, Bill W., was an extremely fervent (really almost religious) advocate of high doses of niacin for treating alcohol addiction. The fact that this seems to be supported, at least in theory, is pretty wild. I am always shocked when things that are viewed strictly as quackery (and I know there is indeed a lot of that) turn out to be validated. A bit like IV vitamin c being totally written off, and now being used in major hospitals to treat sepsis. Anyways, I wonder if anyone had any experiences, or thoughts to share on…
What they were answering
bronzeagemindset · 3 points
The flush is not that bad, lots enjoy it, and so much more cost effective with similar benefits
u/MisterYouAreSoDumb · ND Owner
I am not saying niacin is bad. It's just not nearly as effective as NMN. If you taken our enteric coated NMN with a CD38 inhibitor like ~~hesperidin~~ quercetin, you are going to increase NAD+ way more than any dose of niacin could.