Comment · Fri, September 25, 2020 · ND Owner
NMN, Niacin, NAD +, and Addiction
Original post in this thread
[deleted] · 5 points
I was really fascinated to see studies supporting the idea that NAD therapy could be a used pretty straightforwardly as a treatment for addiction:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278809/
It seems clear that NMN is one of the best oral routes to raise NAD levels, but there also seems to be evidence that straight niacin can raise NAD levels, at least in individuals considered deficient:
https://pubmed.ncbi.nlm.nih.gov/32386566/
The substance itself, and its systemic effects is quite exciting, but even more wild is that the founder of Alcoholics Anonymous, Bill W., was an extremely fervent (really almost religious) advocate of high doses of niacin for treating alcohol addiction. The fact that this seems to be supported, at least in theory, is pretty wild. I am always shocked when things that are viewed strictly as quackery (and I know there is indeed a lot of that) turn out to be validated. A bit like IV vitamin c being totally written off, and now being used in major hospitals to treat sepsis. Anyways, I wonder if anyone had any experiences, or thoughts to share on…
What they were answering
balle2336 · 0 points
Flushing is a side effect? Selectively highlighting only the negatives, like mentioning about flushing and the ER version seems to be a veiled attempt to promote expensive alternatives. I don't mind flushing if price is one tenth and effect is the same.
u/MisterYouAreSoDumb · ND Owner
Yes, flushing is a side effect for many people. Is this really a surprise? Not everyone is pumping iron at the gym. The effect is also not the same. He also asked why someone might use NMN instead of high dose niacin. I answered. That's not selectively highlighting anything. That's a reason why someone might.