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Comment · Mon, July 6, 2020 · Natrium Health & Nootropics Depot

Testing reveals, many CoQ10 / SAMe supplements contain almost no active ingredients, despite label claims.

Original post in this thread

ProperBeat · 284 points

Supplement manufacturer NOW reports that of the 10 CoQ10 and SAMe products it subjected to analytical testing, only a few came close to meeting the label claims. Most products contained nothing useful or very little. The company purchased 10 CoQ10 products and 10 SAMe products and tested them to assess how much of the respective active ingredients they contained.

https://www.nutraingredients-usa.com/Article/2020/05/14/CoQ10-SAMe-products-sold-on-Amazon-fail-potency-tests

What they were answering

Longroadtonowhere_ · 4 points

Why did they expect Pure Encapsulations to fail?

I thought they were one of the best brands, just below like Thorne.

u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot

Pure Encapsulations was a tossup. I gave it 50/50. You guys have to realize just how many brands are fucking you. You have to know just how hard it is to do things right every single time. The complexity, time, and costs to have every single lot perfect every single time is immense. I know what it takes to do, because I live it every day. So I know how the others are cutting corners. I know how business people think and operate. The money I spend on our quality systems is VERY hard to justify from a business perspective. Just understanding the value of proper quality systems is difficult for most business owners to understand, because they are not down in the trenches with their team actually doing this shit. Many supplements companies don't even have their R&D, quality control, and operations departments working directly together on things in that level of detail. So the R&D teams never relay the things to look out for to the quality and operations teams. They don't know that most milk thistle is standardized via UV-VIS, and that always shows around double what an HPLC result would show, because they are not tasked with finding those answers and building it into their operational and quality systems. I have hired people from a bunch of other supplement companies now, and they have told me how they work from the inside. It's totally insane how some of them operate! Sometimes they are straight up told to modify their methods to make things look good when they know they are not. Some of my lab people work for me today because they were told to do that, and they were not comfortable with it. So they quit and came to work for someone that actually cares about the validity of the results, no matter the costs involved.

I know people that don't know me might think that just sounds like I am blowing smoke up people's asses to have them use us, but I am as genuine and honest as they come. Anyone that works with me for long periods comes to understand that. I truly am just here trying to make this industry better, and to get all of you guys to care about this shit! You guys are putting this stuff in your bodies! Everyone here should care about whether or not the quality testing being done on the products you are using are scientifically valid and accurate. If you guys knew the things I know, and had seen the things I have seen, you would not trust any of these brands out there. Even I am surprised sometimes. I truly thought NOW, Life Extension, and Jarrow would pass on the milk thistle. I really did, and I am very disappointed in them because of it.

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