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Comment · Fri, March 10, 2017 · Ceretropic & Nootropics Depot

Synapsa Is Amazing but those GI Issues...Advice?

Original post in this thread

inmy325xi · 5 points

So I'll start off by saying Synapsa has been a great supplement for myself. I've used the Monnieri brand in the past and that came with depression and lethargy.

However, the Synapsa brand noticeable changes my mood, it makes me more calm and collected and I dosed 300mg for 2 weeks before stopping due to stomach pains. But they were horrible and out of the norm and my bowel movements were painful as well.

I stopped dosing but was wondering if there is anything I can do to offset. I know some users reported these issues but they went away but not for myself. Dosed at night, in the mornings, or even with food. Any help?

Edit: Started taking a probiotic called VSL3 and these issues are not happening anymore. Thanks everyone!!

What they were answering

coiniam · 1 points

Thank you for the insight!

I have heard that these mushrooms can increase BDNF levels. Is there a concern with BDNF overexpression if they are taken for an extended period? Can it cause TrkB downregulation?

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

No, there should be no worry about TrkB down-regulation. Lion's Mane more affects NGF, anyway.

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