Comment · Mon, October 3, 2016 · Ceretropic & Nootropics Depot
Magnesium-25 As A Nootropic And True Enhancer Of Cellular Metabolism
Original post in this thread
PeopleProgrammer · 92 points
http://www.sciencedirect.com/science/article/pii/S0223523408003498?np=y
http://pubs.acs.org/doi/abs/10.1021/jp710989d
Due to it's nuclear spin, magnesium-25 is 2.5x as efficient at catalyzing the synthesis of ATP and stabilizing it in the cytosol, than the 9x more abundant isotope; magnesium-24 which has no nuclear spin. Many people are already deficient in magnesium due to a diet high in processed foods. supplementing with isotopically enriched magnesium (meaning more Mg-25 than the naturally more common Mg-24), could provide a strong stimulant effect rather than traditional depressant role of large doses of Mg^2+ displacing Ca^2+ from its ion channel, and result in dramatically increased metabolism and improved functioning in each cell in the body. I incidentally ran into this as I was researching how I could actually put my rational design project into a GMO cell culture line.
What they were answering
PeopleProgrammer · 3 points
You could always sell it as an intranasal spray or subcutaneous injectable solution, in which case you would not need to chelate it. Interestingly enough, the chelation process itself can be somewhat isotopically selective if the limiting reactant is the organic compound. there isnt always that big of a difference between a salt and chelate in terms of bio-availability anyway. ie, Mg sulfate and Threonate are fairly close in terms of their net increase in Mg^2+ levels, iirc.
EDIT: If you dont mind me asking, what did the supplier you found quote you?
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
I have not gotten a quote from them yet. However, I am pretty sure it will be somewhat reasonable, as it comes in larger quantities.