I’m having a little trouble finding information about the safety of sucrosomial magnesium. Could someone help me out?

It is magnesium oxide surrounded by a phospholipid encased by a sucrester. They are essentially fatty acid sucrose esters that act as emulsifiers, which bridge the gap between water and lipid stability. That is ideal for absorption in the GI tract. They are similar in structure to our own cell walls, and aid in absorption through transcellular and paracellular pathways. Basically think of it like a shuttle for the magnesium across the mucous membranes of the GI tract. It is very similar to how Longvida works. That surrounds a curcumin particle with a lecithin and stearic acid matrix instead of a sucrester, but they perform the same function. You can consider a sucrosome a fancy liposome for mineral delivery. They are certified GRAS, and are as safe as taking any magnesium.

Here is an image showing the structure of a Sucrosomial Magnesium particle.

Here is a picture of a Longvida particle from our product page.

You can see the similarities. They just go about the process differently.

Magnesium oxide has the highest elemental magnesium by mass. However, it is not very bioavailable, and causes a laxative effect when supplemented. So most of the higher-bioavailability magnesium forms go about improving that in one of two ways: making a salt or making a chelate. A salt is just when the positive ion (cation) of an acid and the negative ion (anion) of a base ionically bond together. Magnesium oxide is the base, so it accepts protons. It is then bound to an acid like citric acid in magnesium citrate. This creates a magnesium salt. The issue with magnesium salts are that they dissociate in solution. So they separate when you ingest them and solvate. Certain salts are only soluble at certain pH levels, which is how you get different pharmacokinetics from things like tianeptine sodium vs. sulfate. However, salts can only absorb once they dissociate. Then, in magnesium's case, it absorbs through the limited number of ion channels with other minerals in your diet. This is not ideal for supplementation.

On the other hand, chelates bind magnesium to a carrier amino acid, like glycine or threonic acid. This creates magnesium glycinate and L-threonate, respectively. The bonds between magnesium and amino acids are called coordinate bonds. Coordinate bonds are a lot stronger than ionic bonds. So they do not dissociate in solution. This tricks your body into actively shuttling it into your system through the dipeptide transporters, since it is trying to pull in the amino acids from your diet. There are a lot more dipeptide transporters than ion channels. So you can absorb a lot more in the same time. This is why forms like glycinate and L-threonate have better bioavailability. The issue with chelates is twofold. One, the amino acids are bulky, so you get less elemental magnesium (14% for glycinate and 8% for L-threonate). Two, the amino acids have their own effects. This is good if you want those effect, like glycine at night. However, some people get tired if they take magnesium glycinate during the day, due to the glycine. So you have improved bioavailability, but added in other variables that can be good/bad depending on the situation. Enter sucrosomial forms.

Rather than creating an ionically bound salt, or chelating to an amino acid, sucrosomial forms use the structure of the mucous membranes in your GI tract to their advantage. They use this phospholipid sucrester to actively absorb whole particles of magnesium oxide. This allows you to get a higher percentage of elemental magnesium (32-38%) and higher bioavailability. It also doesn't have other amino acids in it affecting the subjective effects. So you are concentrating on just getting as much magnesium into your system as you can. It's a really cool system!