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Comment · Wed, October 5, 2016 · Ceretropic & Nootropics Depot

Magnesium-25 As A Nootropic And True Enhancer Of Cellular Metabolism

Original post in this thread

PeopleProgrammer · 92 points

http://www.sciencedirect.com/science/article/pii/S0223523408003498?np=y

http://pubs.acs.org/doi/abs/10.1021/jp710989d

Due to it's nuclear spin, magnesium-25 is 2.5x as efficient at catalyzing the synthesis of ATP and stabilizing it in the cytosol, than the 9x more abundant isotope; magnesium-24 which has no nuclear spin. Many people are already deficient in magnesium due to a diet high in processed foods. supplementing with isotopically enriched magnesium (meaning more Mg-25 than the naturally more common Mg-24), could provide a strong stimulant effect rather than traditional depressant role of large doses of Mg^2+ displacing Ca^2+ from its ion channel, and result in dramatically increased metabolism and improved functioning in each cell in the body. I incidentally ran into this as I was researching how I could actually put my rational design project into a GMO cell culture line.

What they were answering

Debonaire_Death · 2 points

As I was saying with /u/PeopleProgrammer, you could use an intranasal or subcutaneous ROA to ensure bioavailability, as well as decrease the required dosage and thus reduce the expense for the consumer by allowing for the sale of smaller quantities.

Both intranasal and SubQ ROAs have been used before for MgSO4, I see it being quite feasible.

...Aaaand I now realize PP has already told my idea to you below. Still, I hope this might become a reality. Seems like a fascinating compound.

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

Yeah, it could be an interesting experiment.

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