Comment · Mon, July 25, 2016 · Ceretropic & Nootropics Depot
That feel when you have to give up the nootropic that works well for you because of its potential side effect.
Original post in this thread
tronatula · 15 points
I am not good in English.
A single dose of 3.6g piracetam helps my short term memory better and provide other benefits, and I take 9.6g daily. Yet according to Effect of piracetam, vincamine, vinpocetine, and donepezil on oxidative stress and neurodegeneration induced by aluminum chloride in rats:
These results suggest that while the low therapeutic doses of the nootropic drugs piracetam, vincamine, and vinpocetine display anti-oxidant and neuroptotective effects, their high doses are likely to have prooxidant and proinflammatory properties.
The high dose they use is 300 mg/kg in rat a day, which maybe 3.5g in a 70kg human, while I take 9.6g a day. However, here is another study show piracetam reduces oxidative stress (Piracetam improves mitochondrial dysfunction followingoxidative stress), but I'm still scared my dose is not good.
I have been so sad since reading those studies, cause I am facing a difficult truth: giving up a better me for... a better me? I have been taking high dose piracetam for almost a year.
Could anyone please take a look at th…
What they were answering
tronatula · -1 points
Hi /u/MisterYouAreSoDumb, I have ordered Ceretropic Semax through a reshipper to Vietnam, the package will arrive next week, I'm going to combine semax with piracetam but those studies make me flustered. Would you mind giving me some advices?
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
The oxidative stress study? That just means that higher dosages can exacerbate oxidative stress when combined with a highly toxic compound. Aluminum chloride is a neurotoxin. That study is not saying Piracetam caused issues by itself. All the dosages were taking with aluminum chloride. Don't eat aluminum chloride, and you should be fine.