Bacopa seems controversial here...

Comment · Tue, March 22, 2016 · 8 pts

Bacopa up-regulates your trytophan hydroxylase enzyme. That converts trytophan to 5-HTP. Both 5-HTP and L-DOPA go on to share the same rate-limiting enzyme called aromatic L-amino acid decarboxylase(AAAD). 5-HTP becomes

Comment · Wed, March 23, 2016 · 1 pts

My pleasure!

Comment · Wed, March 23, 2016 · 1 pts

Potentially, yes. Bacopa increases GABA, and up-regulates GABA receptors in the hippocampus.

Comment · Fri, March 25, 2016 · 2 pts

Yeah, the exhausted feeling is because it is lowering dopamine and increasing GABA. You can take something to increase dopamine to counteract it. I would suggest Rhodiola and L-Tyrosine. You could also use Phenylpiraceta

Comment · Sat, March 26, 2016 · 1 pts

My pleasure!

Comment · Fri, September 9, 2016 · 1 pts

No, it does not counteract Modafinil. Bacopa can lower dopamine production over time, not release or binding.

Comment · Fri, September 9, 2016 · 3 pts

Modafinil does not increase dopamine production. Modafinil blocks the dopamine transporter, increasing levels in the synapse for a short period. Production of dopamine itself is not changed.

Comment · Sun, September 11, 2016 · 2 pts

Sure, after a while it might lower dopamine. However, you can always supplement for increased dopamine production. Bacopa just up-regulates tryptophan hydroxylase, which increases 5-HTP production. 5-HTP competes with L-

Comment · Mon, September 12, 2016 · 2 pts

Yes, you can take it while on Modafinil. L-Tyrosine is not a direct stimulating agent. It is just a precursor to L-DOPA, which increase the production of dopamine and norepinephrine. I'd take the L-Tyrosine in the AM and

Comment · Fri, September 16, 2016 · 1 pts

My pleasure!