Comment · Mon, March 21, 2016 · Ceretropic & Nootropics Depot
Citicoline more active than GPC Choline?
Original post in this thread
JoaoAlexandre · 2 points
I've read that Choline gives you a more active focus then GPC Choline. I don't mean the intensity of focus, but the energy. And when I saw Citicholine on a pre-workout supplement (along with Yohimbine HCL) I got to wonder if it is more effective for a pre-workout supplement and focus.
What they were answering
jimmythegreek1 · 2 points
wasn't that based on only one study in rats where they injected it directly in the vascular system of the brain?
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
There are multiple studies out there showing that increasing ACh increases the release of growth hormone and others from the pituitary. Both Citicoline and Alpha-GPC increase ACh. There are even some human studies showing this effect.
Glycerophosphocholine enhances growth hormone secretion and fat oxidation in young adults
The study you are probably referring to was this one: CDP-choline increases plasma ACTH and potentiates the stimulated release of GH, TSH and LH: The cholinergic involvement
That one did use ICV injections in rats. However, the link between increased ACh and increased GH release is fairly well established.