Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. (2016)

Comment · Mon, March 14, 2016 · 7 pts

Full Study: http://journal.frontiersin.org/article/10.3389/fphar.2016.00031/full >Our results suggest that Selank is able to directly influence the expression of genes involved in neurotransmission in nerve cells, and s

Comment · Tue, March 15, 2016 · 9 pts

We are 99% sure we now have real 7,8-DHF. We are just trying to verify that it is pure. There is a little extra peak on the FTIR where solvent would be. So we need proper methods to run it through the HPLC. We are workin

Comment · Tue, March 15, 2016 · 4 pts

My pleasure!

Comment · Tue, March 15, 2016 · 2 pts

Me and my team. We run Ceretropic and Nootropics Depot.

Comment · Tue, March 15, 2016 · 1 pts

Well they are saying that Selank acts allosterically, and alters the expression of various genes that control receptors, transporters, and binding affinities of things like GABA, dopamine, serotonin, and orexin. These ef

Comment · Tue, March 15, 2016 · 1 pts

Are you getting the smaller versions? There are about 60 sprays in each bottle. So if you are taking two sprays of the 200mcg, you could just take one spray of the 400mcg, and have the bottle last longer. If you are taki

Comment · Tue, March 15, 2016 · 2 pts

Yes, that is correct. It is a potent agonist of the TrkB receptor, which is what BDNF binds to.

Comment · Wed, March 16, 2016 · 2 pts

Well I have been trialing an Orexin-A nasal spray for waking up. Haha. So that's convenient!

Comment · Wed, March 16, 2016 · 2 pts

Yes. It is a very fast acting mood boost, and lasts about 2 hours or so. However, you have to take it sublingually to work. The oral bioavailability is low.

Comment · Wed, March 16, 2016 · 2 pts

Sounds good!

Comment · Sat, March 19, 2016 · 1 pts

No, it is mood-boosting because of the TrkB activation, not activation of the reward pathway.

Comment · Sat, March 19, 2016 · 1 pts

Soon!

Comment · Wed, March 23, 2016 · 1 pts

It basically makes me feel more awake and aware. Orexin-A is what is too low in people with narcolepsy.

Comment · Thu, March 24, 2016 · 1 pts

Orexin-A affects wakefulness by modulating dopamine, norepinephrine, histamine, and ACh. That increases alertness and attention while sleep deprived. If you got enough sleep, it will not affect your cognition, though. It

Comment · Tue, March 29, 2016 · 1 pts

Yeah, it basically staves off the mental tiredness you feel form sleep deprivation. I have not tested how long it works for, because I don't want to deprive myself of sleep too long. Haha. I'll work on pricing, and figu

Comment · Wed, June 15, 2016 · 2 pts

It wakes you up and makes you more alert. It's a more natural feeling wakefulness. It works best when you have not had enough sleep. Timeline is dependent on our new card processor, which could be any time from 1 week t