Comment · Thu, January 14, 2016 · Ceretropic & Nootropics Depot
Noopept megadose
Original post in this thread
Aryanking · 1 points
I got some Noopept capsules from PowderCity. I'm not keen on sublingual admin. I've read that bioavailability is around 9-10% orally, So I'm thinking of starting at 100mg orally ... Would this mean approximately 9-10 mg will successfully enter my bloodstream? Whats the downside to megadosing orally to get the desired effect ?
What they were answering
Aryanking · 1 points
Because of all the well supported claims of its 9-10% oral bioavailability by well respected mods like /u/MisterYouAreSoDumb ; if I administer 100mg orally, then approximately 9-10mg will likely enter my bloodstream. Is 9-10mg of (successfully absorbed) Noopept daily considered a large dose?
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
It's not that simple. Oral dosage show different metabolites than other ROAs too. So you can just take 10X the dosage, and expect the same effect. 100mg oral Noopept is not a good idea to start with. Go with 30mg instead, or use 10mg sublingually. Or you can just go with the Russian recommendation, and do 50mg orally. Anecdotes show differing results with that method, though.