Comment · Fri, July 10, 2015 · Ceretropic
DMSO-Dihexa ocular/eyeball delivery
Original post in this thread
dihexa · 5 points
After using Dihexa through different ROIs (IM, oral, transdermal DMSO, through the nose) and at different doses, I am a little frustrated that I haven't had any real 'success'/'breakthroughs' with it (beside a few vivid dreams), unlike others, who have posted their positive results across several forums.
I'm interested in using DMSO (75%) to dissolve what I have left of this hydrophobic peptide and then deliver it ocullarly to achieve maximum bioavailability. Besides IV (which isn't an option for me), there doesn't appear to be any decent ROIs with high enough bioavailability. I can't find much (officially) about the safety of applying DMSO to the eyeballs, which is my major concern... beside this paper excerpt from 1968:
if any single fact has emerged from animal and human studies with DMSO to date, it is that the lens toxicity findings originally reported in dogs and later confirmed in certain other species have no equivalent or counterpart in human therapy utilizing DMSO in generally accepted regimens.
My solution of DMSO-Dihexa would be about 30 drops in total. That's 50mg of Dihexa diluted in ~30 drops of 75% DMSO-saline to then be dropped into my eye/s.
What do you…
What they were answering
lastPharaoh37 · 1 points
based on what is that a bad idea? I assume you are just speaking from common sense but that isn't always right. I am not saying you're wrong; just that you haven't given any basis for it.
u/MisterYouAreSoDumb · Ceretropic
DMSO can be neurotoxic, and makes you smell like rotten creamed corn. You will lose friends, and be alienated from groups; due to your new smell. It will cause your employer give the promotion you were expecting to Carl in accounting. He will then live a happy and fulfilled life, while you will eventually have your desk moved to the basement, and stop receiving paychecks. Don't be forced to move into the basement. Avoid putting DMSO into your eyes.