Comment · Mon, June 1, 2015 · Ceretropic
Sources for delta sleep-inducing peptide (disp)?
Original post in this thread
Saussiche · 9 points
Anyone know if I can get my hands on this? If not, how much would it cost to get a sample manufactured (a la ceretropic)?
What they were answering
Man_O_Man_ · 2 points
I have not read a direct comparison of DSIP to Phospho DSIP stating that it's stronger. However, I found a study about DSIP analogues, which says some of the analogues are stronger: http://www.ncbi.nlm.nih.gov/pubmed/11525128
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Also, this source seems to have much better information on DSIP than elsewhere (Page 62 in particular): https://books.google.com/books?id=rT7clpjUwaEC&pg=PA67&lpg=PA67&dq=Sleep-Inducing+Properties+of+DSIP+Analogs&source=bl&ots=vuYJHtGp0n&sig=gZPx9J8HJEpgktktAM3ZEPeWaKo&hl=en&sa=X&ei=wY9qVbu1EtWwogSNyILoCw&ved=0CDkQ6AEwBA#v=onepage&q=Sleep-Inducing%20Properties%20of%20DSIP%20Analogs&f=false
EDIT: That source doesn't say if P-DSIP is Phosphorylated DSIP (125I-N-Tyr-P-DSIP).
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~~The whole thing is interesting. Some studies show that it helps with sleep when taken soon before bedtime, while others show none what so ever. And it increases body temperature, even though body temperature drops during sleep.~~ The last source says DSIP causes a dip in body temp, which makes more sense. Other sources said it caused body temp to rise.
u/MisterYouAreSoDumb · Ceretropic
Interesting. That group will alter the shape of the peptide, and will most likely change where/how much it binds. This appears to be another rabbit hole that needs jumping into.