Adamax

Comment · Tue, May 8, 2018 · 8 pts

Negative. It's a new peptide we created.

Comment · Tue, May 8, 2018 · 8 pts

It's a peptide we created a couple years ago. I didn't know my team was making the page live yet. I'll go into more detail soon.

Comment · Tue, May 8, 2018 · 10 pts

Google won't have anything, since we created the peptide and I came up with the name. It is essentially Semax which has been N-acetylated and capped on the C-terminus with an adamantyl-glycine moeity. The sequence is Ac-

Comment · Tue, May 8, 2018 · 5 pts

I guess my team put it into stock. LOL The sequence is Ac-MEHFPGP-AG-Nh2

Comment · Tue, May 8, 2018 · 11 pts

It's N-acetyl semax that has been capped on the C-terminus with the adamantane moeity from P21. I've been personally using it for a few years.

Comment · Tue, May 8, 2018 · 6 pts

The adamantane moiety was placed on the C-terminus of P21 to protect it from enzymatic degradation, and to increase its lipid solubility. We just applied that same idea to Semax instead of the CNTF-enhancing DGGL sequenc

Comment · Tue, May 8, 2018 · 9 pts

It's a more stable and lipid-soluble form of Semax.

Comment · Wed, May 9, 2018 · 4 pts

Possibly, yes. However, it will be months at least before that happens.

Comment · Wed, May 9, 2018 · 5 pts

The adamantane moiety is already amidated.

Comment · Wed, May 9, 2018 · 6 pts

Kind of, yes. Basically N-acetyl semax amidate with an adamantane moeity before the amide group on the C-terminus.

Comment · Wed, May 9, 2018 · 2 pts

I don't think we can accurate say one way or another without some formal pharmacokinetic data.

Comment · Thu, May 10, 2018 · 5 pts

You're one of the only people outside of Ceretropic that has ever tried Adamax. Haha

Comment · Thu, May 10, 2018 · 4 pts

Nobody ever accused me of being predictable. Haha. The sheer amount of things we have worked on in the background is kind of crazy. We just stopped publicly discussing/releasing them.

Comment · Wed, May 16, 2018 · 2 pts

I can really only discuss what it should do structurally. It should be more lipid soluble, and pass through lipid membranes like the blood brain barrier better.

Comment · Thu, May 17, 2018 · 1 pts

The amidate is just an amide grouping capping the C-terminus of the peptide. This protects that end of the peptide from ezymatic degradation, and usually makes the peptide less polar.