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Comment · Fri, October 31, 2014 · Ceretropic

Trying Nicotine as a Nootropic

Original post in this thread

selfperfection · 3 points

My favorite nootropic, caffeine, really has not been doing it for me lately. I guess my tolerance has gotten too high. Soon I will try to get it back to normal by going a few days without it. However, I have been reading up on the use of nicotine and a nootropic. I've decided to give it a try. I just purchased a pack of 2mg Nicorette from CVS, and am heading to the library to study. I will let you know how it goes. I also will try to update regularly as I use the remaining 19 pieces in the pack.

EDIT: The first "session" was overall very productive. I've been at the library for about 2 hours, and feel like I could continue, but unfortunately, it closes at 9. I got a fair amount of work done, although I had consumed caffeine and L-theanine earlier (about 2 hours earlier, I was feeling tired so I figured I'd try the nicotine).

EDIT: Second session, about a week later. Not as productive. Could be due to a number of factors. So far there has been no urge to take a piece of nicotine gum, have not noticed any addictive side effects. First impression is that it is basically just a stimulant. No pure nootropic qualities other than it makes you more awake and ready to work as much as caf…

What they were answering

shrillthrill · 6 points

While nicotine has some interesting cognitive benefits and feels good: If you're a health conscious and want to minimise health risks. Nicotine is probably worth avoiding. i.e. it's probably not going to benefit your all round health with chronic use if these are preliminary indicators:

* Nicotine appears to decrease the neuroprotective role of estrogen in both sexes (see Examine.com entry section 11.2) and New evidence of mitochondria dysfunction in the female Alzheimer's disease brain: deficiency of estrogen receptor-β (2012) as hypothetical concern.

* Oral contraceptives and nicotine synergistically exacerbate cerebral ischemic injury in the female brain (2013)

* Nicotine signaling and progression of chronic kidney disease in smokers (2013)

* Nicotine appears to have carcinogenic metabolites produced in human saliva. Adequate Vitamin C is suggested to counteract. ref1 ref2

* Nicotine appears to have detrimental effects on gum tissues ref

* Nicotine also seems to accumulate in melanin: [
Nicotine impact on melanogenesis and antioxidant defense system in HEMn-DP melanocytes (2014)](/r/DrugN…

u/MisterYouAreSoDumb · Ceretropic

I have some cytisine that I got to test out. I'll let you know how it works.

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