Comment · Sat, November 2, 2013 · Ceretropic
Experiences with IDRA-21?
Original post in this thread
nooilovethetropics · 5 points
So I stopped using nootropics about 4 months ago because my experiences were never consistent. Three days ago I got an email from nsn announcing they started carrying an exciting new chemical, IDRA-21 . Because I trust nsn not to carry crap, generally, I purchased a gram on a lark, thinking I'd research it later.
It came in the mail today, and I start looking around, and there's very little info! A couple of scary posts re safety, but no anecdotes or suggestions re dosage.
So what are the thoughts around here? Had anyone tried it? If so, what kind of dosage and what were the effects? Does anyone have an idea of whether alcohol (a few drinks) would have a detrimental effect? Should i just toss the stuff? Thanks!
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · Ceretropic
Don't trust anyone blindly. Don't even trust me without first researching yourself. Even we are going to be bringing out substances that are not for everyone. So doing your own research, and deciding for yourself, is key.
IDRA-21 is too new to the community for you to get the definitive answers you are looking for. I have some on the way to try, so I will be getting a feel for it soon. However, there are a couple things to be aware of.
There is evidence that IDRA-21 exacerbated AMPA excitotoxicity during stroke. This makes sense, as it is a powerful AMPAkine. It seems to not be voltage-dependent, where it will close the channel before too high of Ca^2+ influx into the neuron. So one needs to be careful mixing it with other stimulants that will raise glutamate levels.
As far as dosages are concerned, start low. I'd say start at 5mg to make sure you don't have a bad reaction. Then you can slowly up it to about 25mg.
As far as the anecdotal info you are looking for, I cannot answer that. I would not drink alcohol while on it until you can get a feel for it. I would also abstain from any stimulants, including caffeine, on the days you trial it.