Comment · Mon, September 30, 2013 · Ceretropic
Methamphetamine
What they were answering
[deleted] · 1 points
True that. Especially when you don't like the tastes of certain foods or have allergies - both are a huge hindrance!
Good deal. I've always been interested in trimethylglycine, which is related (well, it's glycine with 3 methyl groups attached to it, haha). Never had the drive to try it, honestly! I'm a big fan of taurine these days though. It seems to modulate both the GABA and glycinergic systems! Definitely helps to take before bed.
That makes sense! Sleep deprivation in general is pretty taxing on the immune system (and the brain!). I hear caffeine suppresses the immune system slightly (mainly due to its non-selectiveness in adenosine receptor antagonism, and certain adenosine receptors play an important role in the immune system..I dunno the details unfortunately!).
Slightly off topic thought, but I wonder - would a noncompetitive a1 / a2a receptor antagonist be a viable replacement for caffeine? Its noncompetitive nature could make it not have the insurmountable tolerance that caffeine can cause. If its half-life was just right, it could help put us right to sleep, too! Theoretical pharmacology makes me giddy.
u/MisterYouAreSoDumb · Ceretropic
Noncompetitive adenosine receptor antagonists could be an interesting avenue to look at. I have not really researched possible ones to use, though.