Methamphetamine

Meth, much like its ever-popular sibling, amphetamine, can't be considered a nootropic, although it would probably be helpful for boosting productivity (especially since it's FDA-approved for the treatment of ADHD).

First, if you're serious about using meth, you should get a prescription for it (much easier said than done, I know...), if for no other reason than to be certain your product meets USP standards in terms of purity. And plus, while I don't know what route of ingestion you have in mind, I can confidently say that oral is going to be safer than insufflation or smoking.

I'd recommend, supplement-wise, that you load up on antioxidants. Don't recall recommended antioxidants aside from melatonin... anyway, know that meth is going to dramatically increase oxidative stress, particularly in the brain - that's probably the most damaging aspect of the drug. Consider taking melatonin before bed each night. Doses in the microgram range are effective, but perhaps your case would warrant a larger dose.

And, really, make sure you get enough sleep. Lack of sleep is more anti-nootropic than any alcohol or cannabis binge, in my experience. It really makes a world of difference.

You should probably steer clear of coffee too, if for no other reason than to put less stress on your heart.

Also, just my advice, but don't ever re-dose. Going down that path even once is such a tempt…