Comment · Sun, August 18, 2013

Can you develop tolerance to antihistamines ?

Original post in this thread

g0rth · 18 points

So, the allergy season has once again struck upon me and was wondering if it is preferable to switch between various antihistamines to have them fully effective. My favorite one has always been fexofenadine, but I found it loose its effectiveness over longer period of use. Last year, I alternated between fexo and diphenhydramine, but the adverse effects of DPH weren't that welcome.

So do you guys know if there's such a thing as tolerance to antihistamines of was it just in my head ?

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb

You most certainly can. I take 4 Zyrtec a day for my mast cell disorder. When it first started, I only had to take one a day. Doctors just tell me to take what I need. They have no idea what causes it, or how to fix it. Fun stuff...

Other MYASD lines in this thread

Related in the archive

Postr/DrugNerdsDec 29, 2012r/Nootropics years

MDMA Supplementation

Ok, I did promise that I would make another post regarding supplementation to mitigate MDMA induced neurotoxicity. I have just been putting it off. Since my last post, I have gathered more information regarding my theory

205270MagnesiumDosing

Postr/DrugNerdsNov 22, 2012r/Nootropics years

MDMA Neurotoxicity Part 1 Metabolites)

This is probably going to be the first in a series of discussions I start about MDMA. There's just too much information for one post. Therefore, I am going to start with one that is very interesting to me: MDMA's metabol

129118Quercetin

Commentr/DrugNerdsAug 10, 2020Nootropics Depot

Forget Plant-Based Medicine, MDMA is Now Made From Crude Oil

Thank god. The harvesting of safrole was a massive cause of deforestation. Using a minuscule amount of petroleum is much more sustainable. This article is stupid. >MAPS did not comment on the infrastructure necessary t

105

Commentr/DrugNerdsNov 29, 2014r/Nootropics years

I found a problem in DrugNerds.

Replying to Trance_Forming · /u/misteryouaresodumb

Yeah, a bunch of people have been messaging me about it. I have always said that I was putting my research out there to help people, and make the use of this amazing substance safer. The best way to do that is to get peo

Commentr/DrugNerdsMar 17, 2020Nootropics Depot

COVID-19: A growing list of new vaccines and therapies in development

Just so everyone is aware, there has never been a vaccine for ANY type of coronavirus. We have never successfully produced a coronavirus vaccine. So people holding out hope that we will have one to market anytime within

Commentr/DrugNerdsMar 20, 2013r/Nootropics years

Coffee and serotonin

http://www.sciencedirect.com/science/article/pii/0024320584900948 >The results suggest that the elevations in brain 5HT and 5HIAA levels produced by caffeine do NOT enhanced 5HT synthesis, despite significant elevations

28Caffeine