Comment · Mon, August 19, 2013

Can you develop tolerance to antihistamines ?

Original post in this thread

g0rth · 18 points

So, the allergy season has once again struck upon me and was wondering if it is preferable to switch between various antihistamines to have them fully effective. My favorite one has always been fexofenadine, but I found it loose its effectiveness over longer period of use. Last year, I alternated between fexo and diphenhydramine, but the adverse effects of DPH weren't that welcome.

So do you guys know if there's such a thing as tolerance to antihistamines of was it just in my head ?

What they were answering

lolsail · 2 points

mast cell disorder

dermatographia/idiopathic urticaria?

u/MisterYouAreSoDumb

Correct, dermatographism.

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