Comment · Tue, July 23, 2013 · Ceretropic
What they were answering
GSV-Culture · 1 points
They do not do the same thing. D-serine is a potent full agonist of NMDA at the glycine binding site. D-cycloserine is only a partial agonist at the glycine site
u/MisterYouAreSoDumb · Ceretropic
Are you suggesting that a partial agonist is doing the same thing as a full agonist?
Comment · Tue, July 23, 2013 · 2 pts
I've tried it. I noticed a little over-stimulation while stacking it with other racetams; particularly AMPA modulators like sunifiram. It's a partial agonist of glutamate, binding to the glycine receptor, so care should
Comment · Tue, July 23, 2013 · 7 pts
They do not do the same thing. D-serine is a potent full agonist of NMDA at the glycine binding site. D-cycloserine is only a partial agonist at the glycine site. This makes D-serine much more dangerous when speaking in
Comment · Tue, July 23, 2013 · 2 pts
Liftmode sent me some by accident, so I was curious. I used it in the normal course of my day, and did not try to combat a phobia. I have only used it a couple times, as I am always cautious with agonist/partial agonists
Comment · Tue, July 23, 2013 · 3 pts
Yeah, I don't see it as very useful in healthy individuals. It definitely makes you feel "off" in a stimulated sort of way. Add in some positive modulation of the AMPA receptors, and you are just asking for excitotoxicit
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