How long prior to MDMA should you take your pre-load? (multivitamins, magnesium and antioxidants)

Comment · Thu, December 27, 2012 · 22 pts

**-Fully chelated magnesium glycinate.** Doctor's Best brand is good. Most brands are shit. (Dose 400mg before and during) **-Alpha lipoic acid.** You can either get racemic ALA, which is still good. Or you can get full

Comment · Thu, December 27, 2012 · 13 pts

**NO!** It inhibits metabolism by CYP3A4, which uses N-demethylation to produce MDA. MDA is **MUCH MUCH** more neurotoxic than MDMA. You should absolutely drink grapefruit juice! MDMA's neurotoxicity is a direct result

Comment · Thu, December 27, 2012 · 2 pts

[Here, link the other picture I made. This one has most of everything on it.](http://imgur.com/aAAhs)

Comment · Thu, December 27, 2012 · 3 pts

In MDMA's case, it should absolutely be used! Higher MDMA serum levels are much safer than it's toxic metabolites. Read my post here: http://www.reddit.com/r/DrugNerds/comments/13lp0b/mdma_neurotoxicity_part_1_metaboli

Comment · Thu, December 27, 2012 · 6 pts

Metabolism of MDMA to MDA in humans is anywhere from 5% to 18%, depending on dosage, re-dosing schedule, body temperature, and a couple other factors. Rats metabolize much more to MDA, due to their CYP2D1 (Their CYP3A4

Comment · Fri, December 28, 2012 · 1 pts

Yes, that will be the only way to prove it. Know anyone? Haha

Comment · Fri, December 28, 2012 · 3 pts

I take CoQ10, but I have yet to try idebenone. When do you take it, and what is your dose?

Comment · Fri, December 28, 2012 · 5 pts

I'm 27, and I only take it every 4-6 months. However, I always take my supplementation. I am telling you guys, it works. I have zero comedown, zero clenching, I can pee, and I have a 2 week long afterglow. My supplementa

Comment · Fri, December 28, 2012 · 2 pts

Correct. But I have spoken to it on other posts, it kills the empathy of the experience. I do not like the feeling of MDMA on any of the racetams. I tried it with noopept last week. It was soooo intense, and all the empa

Comment · Sat, December 29, 2012 · 2 pts

Indeed it is. My comment was more to do with your statement, " I space out my rolls by doing it only like once or twice a year and only really snag some 5HTP after the fact. The rest of this all sounds like some sketchy

Comment · Sat, December 29, 2012 · 3 pts

I never said skepticism was unwarranted. I was calling into question your wording. You have a strange way of trying to engage in productive conversation. I even said: >If that's not the case, I apologize. I was on my p

Comment · Sat, December 29, 2012 · 3 pts

There's no point in arguing semantics. We'll get nowhere. The piracetam was in there because I just copied this from another one of my posts. It does have neuroprotective properties as well, so it's inclusion it's not t