Comment · Sun, December 2, 2012 · Ceretropic
Hypomanic modafinil rebound
Original post in this thread
MisterYouAreSoDumb · 3 points
I had a very interesting interaction a couple days ago. I had been taking 75mg D-modafinil every day for 5 days, while ceasing my caffeine supplementation. I got back home from Thanksgiving in Colorado, and decided to drop the modafinil and return to my normal stack.
In the morning I took:
200mg caffeine
10mg noopept
500mg bacopa
120mg ginkgo
500mg ALCAR
150mg Na-R-ALA
200mg magnesium glycinate
200mg EGCG
500mg quercetin
sublingual B complex
1,600mg piracetam
_________________________________________________
Well this resulted in a first class ticket to hypomaniaville! It must have been a rebound effect from adding caffeine back in with the residual effects from the modafinil. I am pretty certain it has something do do with modafinil's induction of certain CYP450 enzymes. It was not unpleasant, and I was fully aware of what was going on. In fact, it was extremely enjoyable. I had dopamine/serotonin tingles shooting through my head all day long. It literally felt like I had taken MDMA. The next day I kept my stack exactly the same, but it did not lead to the same result. It worked, but more from a focused standpoint.
Anybody else have a similar effect from modafi…
What they were answering
AtomikPi · 1 points
I assumed as much. I would just generally encourage people to use the terms "hypomania" and "mania." Because of the similarity in pronounciation of "hypo" and "hyper" and because some people are not familiar with the term "hypo," there ends up being quite a bit of confusion when people write about mania.
"Mania" should really only be used for full-bore manic episodes with severely reduced sleep, risk-taking behavior, psychotic symptoms, and so on.
u/MisterYouAreSoDumb · Ceretropic
True. I could see that leading to confusion.