Comment · Sun, December 2, 2012 · Ceretropic
Hypomanic modafinil rebound
Original post in this thread
MisterYouAreSoDumb · 3 points
I had a very interesting interaction a couple days ago. I had been taking 75mg D-modafinil every day for 5 days, while ceasing my caffeine supplementation. I got back home from Thanksgiving in Colorado, and decided to drop the modafinil and return to my normal stack.
In the morning I took:
200mg caffeine
10mg noopept
500mg bacopa
120mg ginkgo
500mg ALCAR
150mg Na-R-ALA
200mg magnesium glycinate
200mg EGCG
500mg quercetin
sublingual B complex
1,600mg piracetam
_________________________________________________
Well this resulted in a first class ticket to hypomaniaville! It must have been a rebound effect from adding caffeine back in with the residual effects from the modafinil. I am pretty certain it has something do do with modafinil's induction of certain CYP450 enzymes. It was not unpleasant, and I was fully aware of what was going on. In fact, it was extremely enjoyable. I had dopamine/serotonin tingles shooting through my head all day long. It literally felt like I had taken MDMA. The next day I kept my stack exactly the same, but it did not lead to the same result. It worked, but more from a focused standpoint.
Anybody else have a similar effect from modafi…
What they were answering
beyonsense · 1 points
What's the point of taking Noopept and Piracetam at the same time?
u/MisterYouAreSoDumb · Ceretropic
They work in different manners, and bind to different receptor sub-types. Usually I take oxiracetam in my stack with noopept. I am replacing it with piracetam to see how that affects me differently.
Noopept is a vastly different molecule than piracetam. Oxiracetam and piracetam are very similar, only differing by a hydroxide group.