Archive

Ordering emoxypine

Replying to Ineedpalmtreeliving · Im immunocompromised so definitely immunity, then strength/endurance, cns activation, stress regulation, skin and hair health

I'd keep these: * Microzinc * Reishi * Cordyceps * Tongkat * Epicatechin * Shilajit * ALA (I'd do our OptimALA) * Hesperidin * Bacopa (I'd take our Cognance) * Gotu Kola * Polygala * DLPA * Injuv * White Jelly * Agmatine * Taurine

Alternative good manufacturer for Agmatine?

Replying to VicemanPro · Imgur won't load for me if I'm using my VPN, not sure if its that. But no worries, thanks for the offer! What's the best way to ship it in (or drop off)?

That was it! I was connected to the office VPN. Thanks for the heads up! Wow, those are definitely green! Was Elphaba working on the production line that day? LOL

Alternative good manufacturer for Agmatine?

Replying to VicemanPro · Yup. I've bought from them several times and it was white, but one batch I received was green. [Green agmatine](https://imgur.com/gallery/XrJpwFb)

That image won't load for me for some reason. I'm curious to test it and see what the deal is. Never seen green agmatine!

Alternative good manufacturer for Agmatine?

Replying to VicemanPro · I've still got the green agmatine sulfate I received from Nutricost.

Green? It was green in color? If you send it to us, I will run it through the lab.

Alternative good manufacturer for Agmatine?

Replying to IdaPalamida · Of course, they are too cheap to be good. But agmatine is not any worse than ND agmatine. Same shit

I would be surprised if their agmatine failed as bad as some of their other products. That's true. I suppose I could buy some and run it through the lab to really know for sure.

Alternative good manufacturer for Agmatine?

Replying to BorntobeStrong · Yeah, I had experience with Now Saffron, which was positive. I have yet to try yours and probably will on my next order. Canada post shifted to rotating strikes, so free shipping m…

Free shipping to Canada should be back on Monday. We always give a little time for the backlog to work through before we turn it back on, because people freak out at us over any delays. It's best to wait a little extra time to let backlogs work their way through the system.

Alternative good manufacturer for Agmatine?

Replying to BorntobeStrong · I used to think nutricost was great, because of price and products seemed to work. However I am now turned off and suspicious about quality. I bought nutricost agmatine for example…

Not to beat a dead horse, but you not reacting to Nutricost's saffron is because it contains none of the main bioactive compounds. My other comments on this thread show the data. This type of shit is what gives the supplement industry a bad name. You might have just thought saffr…

Alternative good manufacturer for Agmatine?

Replying to brustik88 · I agree with you. But their solo ingredient supplements are legit. Agmatine is one of them

[Here are the chromatograms from Nutricost's saffron, if you want to see the direct data.](https://imgur.com/a/XIUPNbP) First page is crocins and the second page is safranals. We did not test their agmatine, though. I would be surprised if that failed as bad as some of their othe…

Alternative good manufacturer for Agmatine?

Replying to IdaPalamida · It isnt, actually better than some expensive brands

Actually one of the worst in our testing most of the time. See my comment above. https://reddit.com/r/NootropicsDepot/comments/1o7do2e/alternative_good_manufacturer_for_agmatine/njofsmr/

Alternative good manufacturer for Agmatine?

Replying to brustik88 · I agree with you. But their solo ingredient supplements are legit. Agmatine is one of them

Uhh, be careful assuming that. Here is some saffron testing we just did, and Nutricost had ZERO crocins or safranals in their saffron. [Results Graph](https://cdn11.bigcommerce.com/s-cebedmpn/images/stencil/original/content/img/pdp-value-prop/Saffron-Market-Data-Crocins-Safranal.…

Epicatechin Capsules

Replying to Specialist-Gap6463 · Could you create agmatine capsules produced in this way ? They badly hurt my stomach otherwise

We can certainly look into it. It's not something we have really had requested, but we can do some analysis.

Agmatine drama

Replying to salamanta · Whats with the rumor that agmatine (like all nmda antagonists) raise histamine?

As with everything, it gets complex. The strongest evidence for agmatine's ability to increase histamine comes from a study that found that agmatine can concentration-dependently induce the release of histamine from histamine-storing cells in the stomach. This effect appears to o…

Agmatine drama

Replying to lawndartin · I personally haven’t found a way to take Agmatine without causing severe stomach/GI discomfort. Has anyone figured out the solution for people that have this reaction to Agmatine? …

Have you been checked for H. pylori infection? H. pylori expresses an enzyme called agmatine deiminase (HpAgD), which catalyzes the conversion of agmatine to ammonia. It might be the conversion to ammonia that is upsetting your stomach.

Agmatine drama

Replying to 7e7en87 · [Quote]But then it caused after 3 years of daily usage of chronic gastritis and pain in my colon for a very long time. There are also research papers about it. It started with 1 m…

That post is linking the study I linked above, and misinterpreting the data. The agmatine levels were elevated in that mouse model because the bacteria in the system were producing it. It was not a causative factor. It sounds like that dude had an untreated H. pylori infection th…

Agmatine drama

Replying to daliriuma · Do you know why it’s not allowed to be sold in the Uk? I love Agmatine but does my head in having to risk getting it to arrive from the states , just all seems a bit strange as it’…

Because they consider it a novel food that doesn't have the history of use to exempt it from that process.

Agmatine drama

Where are you seeing this drama? First, it's important to acknowledge that agmatine is a naturally occurring compound produced by beneficial gut bacteria like Lactobacillus and found in some fermented foods. One of the most compelling pieces of evidence supporting agmatine's safe…

The New Nootropics Depot Is Now Live!

Replying to spyguy23 · The site looks great. However, I noticed that not all the user reviews are available for some products. For instance, Agmatine Sulfate capsules had 27 user reviews, but only nine a…

Ohh weird! It's like the next page button is missing. I will send it over to the developers.

Study: Acteoside Improves Muscle Atrophy and Motor Function by Inducing New Myokine Secretion in Chronic Spinal Cord Injury

Replying to adeptus8888 · im already taking OG cistanche 50%, erinamax and Tiger milk. interested in motor function and fine muscle control improvements as a pianist. I've noticed erinamax was particularly …

Andrographis would be one I would look into. [Andrographolide enhances hippocampal BDNF signaling and suppresses neuronal apoptosis, astroglial activation, neuroinflammation, and spatial memory deficits in a rat model of chronic cerebral hypoperfusion](https://link.springer.com/a…

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Replying to TheGermanGuy21 · Thanks for the reply. You mention sedation, but any idea why Cistanche might make some people feel dysphoric/depressed on it, even the next day? Reminded me of how I reacted to Agm…

Yeah, I think 5-HT1B is the most likely mechanism behind that effect you are getting. That receptor is a current target of interest in depression research. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919989/ Think of our Cistanche products as a sliding scale. * Non-Extracted Ci…

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Replying to wavyeggs · That’s a wide area of effect. Interesting, almost overlaps with Agmatine a fair bit. When I started reading “inflammation, anti-oxidant..” I was like that’s not really unique then …

The agmatine connection is interesting! I had not really thought about it like that, but I guess the mood effects do share some parallels.

Order cognance on the 25th of Nov, ordering from CA and hasn’t received it till now. Usually takes 16 days and ND support has been helpful in the past. Been patient for the tickler for a while now but can someone send help! Order number is 1560835. Thank you

Replying to Miizuji · I actually emailed a document with all of the banned substances for ROK import to your support team when I was dealing with this myself. You’d be surprised what’s on there lol. #…

Wait wait, are you serious?!? There is tons of normal shit on here! Berberine, citicoline, DHEA, icariin, ALCAR, ALA, 5-HTP, agmatine, kava, citrulline, shilajit, andrographis, MAGNESIUM CITRATE... WTF?!?

Does Pyroglutamic Acid increase Glutamate?

Replying to IncreasinglyTrippy · Fascinating. I think it’s been really helpful for my anxiety/adhd. That or Agmatine, or both. Trying to pin it down and understand it. Pyroglutamic acid doesn’t interfere with sl…

Well the Alcohol Defense has glycine in there to try to counteract that. It might affect some people's sleep, but honestly I have not personally tried it before bed on its own.

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Replying to Experienced8 · I appreciate the response. I've used caffeine for a LONG time. Is the groggy/fatigue from substances like glycine, agmatine, magnesium a sign that it's actually working?

Working in what way?

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Replying to Experienced8 · Is it possible that agmatine, magnesium, glycine (which affect NDMA) can make you MORE tired before it starts making stimulants more effective again? I ask because even taking …

Glycine can absolutely do that. However, collagen is over 30% glycine. This means your 20g collagen dose is giving you over 6 grams of glycine. You are getting less than 350mg of glycine in a dose of Clarimag, so it will be nowhere near as strong.

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Replying to JBM2311 · Any clue how much agmatine is needed for reducing tolerance? Would my 500mg daily before bed be enough?

It really depends on the person. I would say take Clairmag in the morning, then 500mg of agmatine by itself in the evening. Many people are deficient in magnesium, and ensuring your levels stay solid will help tolerance from getting out of control. This will make the larger agmat…