🎙️Lion's Mane Mushroom Q&A | Post Your Questions From Our Latest Podcast Episode!🎧

I've spent millions of dollars on this mushroom project over the past 8 years. I've been sinking TONS of resources into trying to solve the science, without knowing if it would ever lead to a product we could make money on. Go search any scientific papers on erinacines/hericenones and lion's mane, and we have likely spoke to them. Some of them were really cool, and willing to talk to us. Others were very protective of what they thought was their intellectual property, not knowing we already recreated everything they did in our lab. I have some of the best scientists in the world working on our mushroom project. We've discovered some things that are likely going to really change the state of the science on lion's mane. We have discovered erinacines in the fruiting bodies. We have discovered new compounds never before found in mushrooms. We've discovered a ton about how lion's mane grows, how different substrates affect it, and how various stressors affect the actives in it. We've been working with other mushroom grow operations in the US, like Southwest Mushrooms and MycTyson, to find different species and strains of lion's mane to cultivate. We have a bunch of different strains and species growing at our facility, including wild species others might not have even seen. When I say we are doing science nobody else is, most people don't really realize just what that means. I can say without a doubt, we are one of, if not the most, advanced mushroom labs in the world. It's just we do a lot of the science quietly in the background, and only talk about it when we feel it is time. We just need to do a better job of showing people what we are doing. That's what our new video series is attempting to do. We will be doing a lot more in the future. We've even created completely new extraction methods that nobody else in the world is even talking about, much less attempting. I have been beta testing those extracts myself, and we have some really really cool stuff in store!

I am excited about your future mushroom products with different bioactives from mycelium and fruiting bodies. Several interesting compounds there. https://www.fungalbiotec.org/pdf/FGBT_1_2_2.pdf

As am I! Stay tuned, because we have some really cool data on the fruiting bodies coming out. We are also going to be partnering with Chromadex and a couple other labs to submit a paper proposing the renaming of the compounds in lion's mane. Whomever named some of these was smoking crack! There are erinacines that are closer in structure to hericenones, and vice versa. Then you have erinacerins, hericerins, and hericenes who's naming makes zero sense sometimes. Just in the paper you linked there are some. Look at hericenone A, hericenone H, N-de-phenethyl isohericerin, and corallacin A... They all share very similar structures, but they were named as different classes of compounds? Makes zero sense! Then look at hericene A and hericenone C. Why is one a hericene and one a hericenone? The most obvious answer would be the ketone in the hericenone, right? Then look at hericenone J. No ketone group! So what makes a hericenone different than a hericene if not for the ketone, when some of the hericenones don't have it? The naming scheme is all over the place, and I think it needs to be redone and simplified to group things based on their structural similarity. Chromadex agrees with us, so I think we are going to collaborate on a paper proposing that.

Our mushroom project isn't just for lion's mane, either. We are doing a lot with other mushrooms as well. We are designing a better assay for beta-glucans, as the current one is insufficient to detect spiking with cheap yeast-based or oat-based beta-glucans. We are also designing a better assay in general for marker compounds unique to mushrooms, to make a better measure of the quality of mushrooms as a whole. The current "total beta-glucan" number is just not good enough. So we have a lot of cool stuff coming on the mushroom front!