Comment · Thu, August 17, 2023 · ND Owner
🎙️Lion's Mane Mushroom Q&A | Post Your Questions From Our Latest Podcast Episode!🎧
Original post in this thread
NootropicsDepotGuru · 18 points
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Our latest episode of the In Search of Insight podcast is a deep dive into our new Lion’s Mane Mycelium supplement. Emiel, James, and Erika discuss building out Omnient labs, developing our Erinacine A standardization process, and the mechanisms of action that make this Lion’s Mane Mycelium powerful for nerve health and cognition.
Have you watched the new episode yet? We want to hear your questions! Post your question in the thread below and tag Emiel u/Pretty-Chill or u/Omnient_Labs so you can learn more about Lion’s Mane Mushroom, its health benefits, and why this mycelium supplement stands out from the crowd.
Watch this month's podcast episode on YouTube and Spotify, and listen on Soundcloud, [Apple Podcasts](https://podcasts.apple.com/us/podcast/in-search-of-insight/id1…
What they were answering
lewanay · 2 points
That's a good point. I'll stick with my 2.5-5 mg per day for now to get the most bang for buck.
Follow up question, do you know what could contribute to the immediate effects people are reporting? Shouldn't actual changes in NGF take weeks if not months, which is one of the reason why trials are conducted for that long. I am assuming there is some anti-inflammatory component to the beta glucans in all mushrooms that may be having an impact.
u/MisterYouAreSoDumb · ND Owner
In this study, we examined the effects of erinacine A on the production of NGF and catecholamines which stimulate NGF synthesis in the brain of rats. Rats were treated with erinacine A by intubation for the first 3 weeks from birth to weaning and intragastrically from weeks 4 to 5. Rats treated with this compound had increased levels of both noradrenaline and homovanillic acid in the locus coeruleus (LC) at 4 weeks of age and increased levels of NGF in both LC and hippocampus at 5 weeks of age. The effects of erinacine A were confirmed in the central nervous system in rats.
So erinacine-A increases norepinephrine and homovanillic acid in the locus coeruleus, which is likely why some people are feeling stimulated by it. There are also other things in Erinamax other than erinacine-A that will be causing effects. We have identified other erinacines in there, but are still working on quantifying them.