Comment · Fri, August 26, 2022 · ND Owner
Apigenin cleared amyloid plaque in a mouse study
Original post in this thread
redditinface · 32 points
A study in Brain published this week showed that "mice treated with either apigenin or sulphaquinoxaline cleared amyloid beta significantly faster than those treated with either of the two inactive substances." (The quote is from this article summary.)
Though you all would be interested to know!
What they were answering
Careful-Cobbler-8359 · 13 points
Why care about amyloid plaques following the recent retraction/controversy in AD research?
u/MisterYouAreSoDumb · ND Owner
Amyloid plaques are still correlated with disease progression. It's just not the smoking gun cause it was made out to be. People with Alzheimer's clearly have amyloid plaques building up. That's not at question. Whether the plaques are the cause or a symptom of the disease is. It's complicated, and the recent Lesné papers being discredited is only part of it.
https://www.science.org/content/blog-post/faked-beta-amyloid-data-what-does-it-mean
You should still care about amyloid plaques. Reducing them can only be a good thing. Is it the primary target to cure Alzheimer's? Perhaps not. Are you going to use apigenin to cure Alzheimer's? Absolutely not.