Comment · Fri, July 22, 2022 · ND Owner
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NDSocialMedia · 44 points
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What they were answering
eamonn123 · 7 points
Oh awesome! Could you help me a question, will taking a NMDA antagonist block some dopaminergic effects of other compounds? Would Agmatine block the effects of coffee? Would magnesium block the effects of other dopaminergic stimulants? Thanks! Your amazing!
u/MisterYouAreSoDumb · ND Owner
Not meaningfully so at these doses. Taking a larger dose of agmatine at the same time as something like amphetamine might mute the effects a bit, but not this dose. What I would suggest in those cases it take Clairmag in the morning, and then take 250-500mg of agmatine sulfate in the evening. That will spread the larger agmatine dose out from the stimulant dose, and give you the best of tolerance management without it acutely affecting the primary stimulant effects during the day.