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Comment · Sun, June 12, 2022 · Natrium Health & Nootropics Depot

Please be cautious on orders from Botany.bio - mistakenly labeled (and therefore adulterated unknown substance) from product found in my last order.

What they were answering

thaw4188 · 1 points

There is room for improvement in your label disclosures.

Take for example your alpha-gpc 50%

Some makers do it without silicon dioxide (or at least they claim).

You list the silica on your label but you don't say what percentage of the product it is. Up to 2% is allowed by FDA. That's a lot of silica and shouldn't be allowed but some manufacturers happily take advantage of it because it's literally dirt cheap padding profit for product weight

So it is 0.5% or 2%? Your label doesn't disclose.

adding: even better (worse?) example, what's the other 1% in your alpha-gpc 99%? Label doesn't say, silica? calcium-phosphate? Not on the product page, not on the spec-sheet, not on the label. No disclosure.

This is why only FDA lab with complete content analysis is going to make sure there is full disclosure to consumers.

u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot

Everyone just lies. We don't add silicon dioxide for shits and giggles. It's crucial to that product flowing on machines and staying stable in powder. Alpha-GPC is VERY hygroscopic. It's one of the most hygroscopic things out there. It needs an excipient for it to properly flow on machines and stay stable. Anyone claiming it doesn't is lying. We are cGMP certified, not just compliant. We got a perfect score on both our cGMP audit and ISO audit. Perfect score. Not a single finding. All our production and formulation processes are in compliance with FDA regulations. We don't put more than we need to on anything, and we certainly don't put more than is legally allowed by regulations. If we can not put extra things, we do that every time. Why add more complexity if it is not needed. We try to remove fillers and excipients wherever we can, and we really do try super hard to do that. That's because I personally would just like to not add things if we don't need to, but also customers read all sorts of stupid shit on pseudoscientific blogs that cause us problems. Then our competitors just lie and leave things off the label, when we test and know they have them in there, and we have to explain to customers the science of why it is needed. If I can avoid all that, and save myself and my support team the headache of another magnesium stearate or silicon dioxide email coming in from someone who just read a Food Babe article, you are damn right I will! However, sometimes they are just needed to accurately formulate, fill, or stabilize a product.

The 99% alpha-GPC is just alpha GPC. We don't put anything else in there. The 99% is the standardization for the assay. That doesn't mean we just chuck 1% other shit in there for fun. There are literally no other ingredients to disclose. We are just very particular and clear with our labeling, to be fully compliant with all regulations. If we have a raw material that is 97%, we list it as that. If you do analytical chemistry enough, you know nothing is ever 100%. There is always water left in there, along with salts like phosphate, sodium, magnesium, etc. from the water used in processing. We have specs for all those, and big internal spec sheets and COAs analyzing every single batch to ensure they meet them. That's also the minimum spec.

Here is a UPLC-MS chromatogram from a batch of our 99% GPC

You can see it was 101% pure compared to the Sigma Aldrich reference standard. Many times our batch is more pure than the reference standard, and in some cases the reference standard is less pure than claimed. This is why we often buy reference standard from multiple placed to get extra confirmation. Orthogonal verification is always what we do. Science is never exact. There are always method/methodology uncertainties, detection limits, matrix interferences, etc.

What do you mean FDA lab? The FDA doesn't run or certify labs. ISO certifies labs. We are ISO 17025:2017 certified with a perfect score. It literally doesn't get better than that.

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