Comment · Wed, November 24, 2021 · Natrium Health & Nootropics Depot
Possible Magnesium Glycinate Withdrawal
Original post in this thread
jrm523 · 7 points
TLDR: I've been taking Magnesium Glycinate for years and recently stopped to take a break and have felt like crap.
Two or three years ago (maybe longer) I started taking high quality (ND) Magnesium Glycinate every night. Recently I ran out and decided to take a 2-3 week break (for the first time ever). A few days after stopping, I had a very uneasy feeling throughout the day. It was like a weird form of Anxiety and I ended up getting a migraine headache. The following day I ended up getting another headache that was slightly less painful. I took some magnesium that evening and the next day I felt great. I didn't take any the following night and felt like crap again the today.
I was just sitting on my couch contemplating why I have been feeling bad this week and realized that it could be due to stopping the magnesium supplement. I say "could be" because I don't know for sure. However, stopping magnesium was the only major change that I have made.
I realize some people will most likely say it's not withdrawal and it's just the feeling of baseline. I can assure you that it's worse than baseline (although manageable).
I originally had a RBC blood test and was just below the minim…
What they were answering
jrm523 · 2 points
Thanks for your reply. Glad to know I'm not going crazy 🤣.. What's your thoughts regarding potassium? I'm assuming it would be easy to hypothesize it throws your electrolytes out of balance and your body attempts to compensate for the sudden lack of magnesium intake?
One thing I forgot to mention is that my wife takes them too but has been taking them regularly for less time than me. I don't think she has experienced any negative effects from this break but I will have to ask her to be sure.
u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot
Yeah, I think it's throwing the balance of electrolytes off, and the sudden lack of magnesium tips it back the other direction too quickly. Potassium actually has calming effects, too. Many people overlook that aspect. They think magnesium is the calming electrolyte, but potassium plays a role too.
https://sci-hub.se/10.1111/j.1399-3054.2007.01033.x
https://sci-hub.se/10.1111/j.1751-7176.2008.08575.x
https://www.nature.com/articles/s41440-018-0131-4
https://link.springer.com/article/10.1007/s11325-021-02444-7
I think a lot of us are neglecting potassium when we are supplementing magnesium. This could be why some people are finding a rebound effect when ceasing.